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NCK adaptor protein 1

Known as: Nck protein, NCK-alpha protein, Nck-1 protein 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Adaptor Proteins, Signal TransducingOncogene Proteins
NCK1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain
Activation of the T cell receptor (TCR) results in binding of the adapter protein Nck (noncatalytic region of tyrosine kinase) to… Expand
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2020
2020
EspFu-Mediated Actin Assembly Enhances Enteropathogenic Escherichia coli Adherence and Activates Host Cell Inflammatory Signaling Pathways
EPEC is among the leading causes of diarrheal disease worldwide. The colonization of the gut mucosa by EPEC results in actin… Expand
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2019
2019
Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion
Podosomes are membrane‐bound adhesive structures formed by actin remodeling. They are capable of extracellular matrix (ECM… Expand
2014
2014
Ubiquitylation‐dependent downregulation of Nck regulates its functional activity
The Nck adapter protein is involved in key cellular functions, such as actin polymerization and reorganization, serving as a… Expand
Review
2013
Review
2013
VEGFA and tumour angiogenesis
In this review we summarize the current understanding of signal transduction downstream of vascular endothelial growth factor A… Expand
2011
2011
Studies of novel interactions between Nck and VAV SH3 domains
Following T-cell antigen receptor (TCR) engagement, a multi-molecular complex consisting of SLP-76, Nck, and VAV1 is formed and… Expand
2007
2007
Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress
Vascular endothelial cells are continuously exposed to mechanical and chemical stimuli, such as shear stress and VEGF… Expand
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2007
2007
Nckβ Adapter Controls Neuritogenesis by Maintaining the Cellular Paxillin Level
ABSTRACT The SH2/SH3 adapter Nck has an evolutionarily conserved role in neurons, linking the cell surface signals to actin… Expand
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Highly Cited
2001
Highly Cited
2001
Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).
We have previously shown that the Drosophila Ste20 kinase encoded by misshapen (msn) is an essential gene in Drosophila… Expand
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1999
1999
The Drosophila SH2-SH3 adapter protein Dock is expressed in embryonic axons and facilitates synapse formation by the RP3 motoneuron.
The Dock SH2-SH3 domain adapter protein, a homolog of the mammalian Nck oncoprotein, is required for axon guidance and target… Expand
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