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NCI-H226

A squamous cell carcinoma cell line established in 1980 from the pleural effusion of a male patient with lung carcinoma.
National Institutes of Health

Papers overview

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2015
2015
SL-801, a Novel, Reversible Inhibitor of Exportin-1 (XPO1) / Chromosome Region Maintenance-1 (CRM1) with Broad and Potent Anti-Cancer Activity
XPO1/CRM1, the principal nuclear export protein in eukaryotic cells, is required for the nuclear-cytoplasmic transport of both… 
2014
2014
Synthesis of Heterocyclic Triads by Pd-Catalyzed Cross-Couplings and Evaluation of Their Cell-Specific Toxicity Profile
Two complementary approaches for the preparation of linked 5-membered heterocycles were developed. The Pd-catalyzed Suzuki… 
2010
2010
QSAR modeling, synthesis and bioassay of diverse leukemia RPMI-8226 cell line active agents.
2008
2008
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226.
2007
2007
Protein profile of human lung squamous carcinoma cell line NCI-H226.
OBJECTIVE To construct a database of human lung squamous carcinoma cell line NCI-H226 and to facilitate discovery of novel… 
2003
2003
Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating…
Highly Cited
2002
Highly Cited
2002
Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin.
Several tumors, including mesothelioma and ovarian cancer, can overexpress mesothelin, a glycosylphosphatidylinositol-linked… 
Highly Cited
1997
Highly Cited
1997
Anti‐tumor Efficacy of Paclitaxel against Human Lung Cancer Xenografts
We examined paclitaxel for anti‐tumor activity against human lung cancer xenografts in nude mice and compared its efficacy with… 
1996
1996
Effect of suramin on squamous differentiation and apoptosis in three human non‐small cell lung cancer cell lines
Non‐small cell lung cancer (NSCLC) is fatal in approximately 90% of all cases due to the failure of systemic therapy, secondary… 
1995
1995
Insulin-like growth factor-I is an autocrine regulator for the brain metastatic variant of a human non-small cell lung cell line.
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