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NC 1100

Known as: NC-1100 
 
National Institutes of Health

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1 relation

Broader (1)

tamolarizine

Papers overview

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1995
1995
Synthesis and structure-activity relationships of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols as new calcium blockers.
A series of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols (4) was synthesized and evaluated for calcium entry-blocking activity… Expand
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1993
1993
[Effects of NC-1100, a calcium channel blocker, on experimental cerebral ischemia/anoxia in rodents].
The anti-ischemic and anoxic effects of NC-1100, a piperazine type calcium channel blocker, were investigated in various cerebral… Expand
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1992
1992
Attenuation of ischemic and postischemic damage to brain metabolism and circulation by a novel Ca2+ channel antagonist, NC-1100, in spontaneously hypertensive rats.
We investigated the effect of a newly synthesized Ca2+ channel antagonist, NC-1100, on cerebral blood flow (CBF) and metabolism… Expand
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1992
1992
A new type of Ca2+ channel blocker, NC-1100, inhibits the low- and high-threshold Ca2+ currents in the rat CNS neurons
The effect of a new type of organic Ca2+ channel blocker, NC-1100 [(+/-)-1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl… Expand
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1992
1992
Calcium entry blocker ameliorates ischemic neuronal damage in monkey hippocampus
Effects of treatment with (+/-)-1-(3,4-dimethoxyphenyl)-2-(4- diphenylmethylpiperazinyl)ethanol dihydrochloride (NC-1100), a… Expand
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1991
1991
[Effects of 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl)ethanol dihydrochloride (NC-1100) on the central nervous system].
The effects of NC-1100 on the central nervous system were analyzed behaviorally and electroencephalographically in mice, rabbits… Expand
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1990
1990
Stereoselectivity of NC-1100, a Ca-entry blocker.
1. Stereoselectivity of NC-1100 in Ca-entry blocking activity was tested in the guinea pig taenia caecum. 2. Racemic, (-)- and… Expand
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1989
1989
Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone…
Effects of oral administration of NC-1100 on the metabolism of neuroactive amino acids in rat brain were studied using stroke… Expand
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1989
1989
[Behavioral effects of NC-1100, 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride--on ambulatory activity, discrete lever-press response and shuttle avoidance response…
Single administration of NC-1100 (3, 10 or 30 mg/kg, p.o.) produced no marked change in the ambulatory activity and discrete… Expand
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1986
1986
Selectivity of cerebral vasodilators on basilar arteries.
Ca-antagonistic activities of cerebral vasodilators, nicardipine and 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl… Expand
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