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NC 1100

Known as: NC-1100 
 
National Institutes of Health

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1 relation

Broader (1)

tamolarizine

Papers overview

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1995
1995
Physiological Results of Monkey Brain Ischemia, and Protection by a Calcium Blocker
Physiological and histological investigation was undertaken to examine dynamic and metabolic changes due to transient ischemic… Expand
1995
1995
Synthesis and structure-activity relationships of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols as new calcium blockers.
A series of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols (4) was synthesized and evaluated for calcium entry-blocking activity… Expand
1992
1992
A new type of Ca2+ channel blocker, NC-1100, inhibits the low- and high-threshold Ca2+ currents in the rat CNS neurons
The effect of a new type of organic Ca2+ channel blocker, NC-1100 [(+/-)-1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl… Expand
1992
1992
Attenuation of ischemic and postischemic damage to brain metabolism and circulation by a novel Ca2+ channel antagonist, NC-1100, in spontaneously hypertensive rats.
We investigated the effect of a newly synthesized Ca2+ channel antagonist, NC-1100, on cerebral blood flow (CBF) and metabolism… Expand
1992
1992
Calcium entry blocker ameliorates ischemic neuronal damage in monkey hippocampus
Effects of treatment with (+/-)-1-(3,4-dimethoxyphenyl)-2-(4- diphenylmethylpiperazinyl)ethanol dihydrochloride (NC-1100), a… Expand
1991
1991
[Effects of 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl)ethanol dihydrochloride (NC-1100) on the central nervous system].
The effects of NC-1100 on the central nervous system were analyzed behaviorally and electroencephalographically in mice, rabbits… Expand
1990
1990
Stereoselectivity of NC-1100, a Ca-entry blocker.
1. Stereoselectivity of NC-1100 in Ca-entry blocking activity was tested in the guinea pig taenia caecum. 2. Racemic, (-)- and… Expand
1989
1989
Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone…
Effects of oral administration of NC-1100 on the metabolism of neuroactive amino acids in rat brain were studied using stroke… Expand
1989
1989
Cardiovascular effects of 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol and possible mechanisms involved.
Cardiovascular effects of NC-1100 (1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl)ethanol and possible modes of action… Expand
1986
1986
Selectivity of cerebral vasodilators on basilar arteries.
Ca-antagonistic activities of cerebral vasodilators, nicardipine and 1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl… Expand
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