N-acetylsphingosine

Known as: C2-ceramide, N-Acetyl-D-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]acetamide 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
MicroRNAs (miRNA) are noncoding RNAs that regulate multiple cellular processes, including proliferation and apoptosis. We used… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Beclin 1 was originally identified as a novel Bcl-2-interacting protein, but co-immunoprecipitation studies suggest that the… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Glucotoxicity and lipotoxicity contribute to the impaired beta-cell function observed in type 2 diabetes. Here we examine the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Neuronal apoptosis induced in cortical cultures by exposure to serum deprivation, staurosporine, nifedipine, or C2-ceramide was… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Like obese humans, Zucker diabetic fatty (ZDF) rats exhibit early beta cell compensation for insulin resistance (4-fold beta cell… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The sphingomyelin derivative ceramide is a signaling molecule implicated in numerous physiological events. Recently published… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The transcription factor NF-kappaB is expressed in neurons wherein it is activated in response to a variety of stress- and injury… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Fas is a cell surface receptor that transduces cell death signals when cross-linked by agonist antibodies or by fas ligand. In… (More)
  • figure 2
  • figure 3
  • figure 4
  • table 1
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Intracellular pathways leading from membrane receptor engagement to apoptotic cell death are still poorly characterized. We… (More)
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Ceramide activates a cytosolic protein phosphatase present in rat T9 glioma cells and rat brain. Ceramide-activated protein… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?