Skip to search formSkip to main contentSkip to account menu

N-acetylsphingosine

Known as: C2-ceramide, N-Acetyl-D-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]acetamide 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Enzyme InhibitorsPlatelet Aggregation InhibitorsSphingosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Singlet Oxygen-induced Attenuation of Growth Factor Signaling: Possible Role of Ceramides
Singlet oxygen, an electronically excited form of molecular oxygen, is a primary mediator of the activation of stress-activated… 
Highly Cited
2003
Highly Cited
2003
Pituitary adenylate cyclase‐activating polypeptide prevents C2‐ceramide‐induced apoptosis of cerebellar granule cells
The sphingolipid metabolites, ceramides, are critical mediators of the cellular stress response and play an important role in the… 
Highly Cited
2003
Highly Cited
2003
Ceramide Enhances Cholesterol Efflux to Apolipoprotein A-I by Increasing the Cell Surface Presence of ATP-binding Cassette Transporter A1*
It is widely accepted that functional ATP-binding cassette transporter A1 (ABCA1) is critical for the formation of nascent high… 
Highly Cited
1999
Highly Cited
1999
Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway.
Immunoregulation of lymphocytes and macrophages in the peripheral immune system is achieved in part by activation-induced cell… 
1999
1999
Potentiation by vitamin D analogs of TNFα and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2
Synthetic analogs of vitamin D induce apoptosis in cultured breast cancer cells and cause regression of experimentally-induced… 
Highly Cited
1999
Highly Cited
1999
Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration.
To investigate the mechanisms of H2O2 adaptation in mammalian cells, we exposed human U937 leukemia cells to 0.05 mM H2O2. This… 
Highly Cited
1999
Highly Cited
1999
Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells.
Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein.
BACKGROUND & AIMS Tumor necrosis factor alpha (TNF-alpha) inhibits collagen gene expression in cultured fibroblasts. By binding… 
Highly Cited
1995
Highly Cited
1995
The Dimeric and Catalytic Subunit Forms of Protein Phosphatase 2A from Rat Brain Are Stimulated by C2-Ceramide (*)
Protein phosphatase 2A (PP-2A) is a heterotrimeric enzyme consisting of a catalytic (C) subunit and A and B regulatory subunits… 
Highly Cited
1994
Highly Cited
1994
Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)