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Because it is generally accepted that a high percentage of poorly motile or immotile sperm will adversely affect male fertility… Expand Early in development, a part of the embryo is set aside to become the germ cell lineage that will ultimately differentiate to… Expand Studies of human genetic diseases have suggested a higher mutation rate in males than in females and the male-to-female ratio… Expand Deletions of the DAZ gene family in distal Yq11 are always associated with deletions of the azoospermia factor c (AZFc) region… Expand The DAZ genes are candidate fertility factors that lie within the human Y chromosome's AZFc region, whose deletion is a common… Expand Abstract The human DAZ gene family is expressed in germ cells and consists of a cluster of nearly identical DAZ (deleted in… Expand We have identified a localized RNA component of Xenopus germ plasm. This RNA, Xdazl (Xenopus DAZ-like), encodes a protein… Expand It is widely believed that most or all Y–chromosomal genes were once shared with the X chromosome. The DAZ gene is a candidate… Expand We have isolated a homologue of the human Y linked DAZ (deleted in azoospermia) gene from mouse. This gene, Dazla (Daz like… Expand We have detected deletions of portions of the Y chromosome long arm in 12 of 89 men with azoospermia (no sperm in semen). No Y… Expand