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Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11.
TLDR
The presence of not one but three spermatogenesis loci in Yq11 is proposed and that each locus is active during a different phase of male germ cell development.
The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology.
TLDR
This work presents a detailed description of the structure-function relationships and models of FSH-FSH Receptor interaction, and some of the mechanisms behind the interaction between the FSH and FSH receptor have been described.
Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure
TLDR
It is concluded that a mutation in the follicle-stimulating hormone receptor gene causes hypergonadotropic ovarian dysgenesis in multiplex affected families and that the mutation causes ODG in these families.
Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations.
The new ISA, ISSAM, EAU, EAA and ASA recommendations on the investigation, treatment and monitoring of late-onset hypogonadism in males provide updated evidence-based information for clinicians who
Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype.
TLDR
Clinical findings demonstrate that the ovarian response to FSH stimulation depends on the FSHR genotype, and the number of ampoules needed could be predicted from a linear combination of both the type of polymorphism and basal FSH levels.
Andrology : male reproductive health and dysfunction
Scope and Goals * Biology of Reproduction,- Physiologym * Sperm Maturation and Fertilization * Classification of Andrological Disorders * Diagnosis of Male Infertility and Hypogonadism * Diseases of
Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations.
TLDR
This research presents a meta-analysis of 129 cases of meningitis in mice over a 12-month period and shows clear trends in progeria and in particular in cases of high prolapse preoperatively and during the course of pregnancy.
Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis.
TLDR
The frequency of gr/gr deletions is not significantly increased in men with oligo-/azoospermia, indicating that they are not sufficient per se to cause spermatogenetic impairment and infertility.
Reproductive functions of the ageing male.
TLDR
Semen volume, sperm motility and sperm morphology decrease with age, whereas the data concerning sperm concentration are conflicting, and age-related changes of semen parameters reflect the histological modifications which are found to varying degrees in individual testes.
Long-term effect of testosterone therapy on bone mineral density in hypogonadal men.
TLDR
In hypogonadal men, BMD can be normalized and maintained in the normal range by continuous, long term testosterone substitution, and is seen during the first year of treatment in previously untreated patients with low initial BMD.
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