Myeloid Leukemia

Known as: LEUKEMIA, GRANULOCYTIC, MALIGNANT, Myelocytic Leukemias, Unspecified myeloid leukemia 
A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are… (More)

Topic mentions per year

Topic mentions per year

1936-2017
010002000300019362016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Myelodysplastic syndrome (MDS) is a clonal blood disorder characterized by ineffective hematopoiesis, cytopenias, dysplasia and… (More)
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Review
2015
Review
2015
INTRODUCTION Immune checkpoints are regulatory pathways induced in activated T lymphocytes that regulate antigen responsiveness… (More)
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Highly Cited
2010
Highly Cited
2010
New studies reveal that 20% of individuals with acute myeloid leukemia harbor somatic mutations in DNMT3A (encoding DNA… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The full complement of DNA mutations that are responsible for the pathogenesis of acute myeloid leukemia (AML) is not… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Mutations occur in several genes in cytogenetically normal acute myeloid leukemia (AML) cells: the nucleophosmin gene… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The cause of chronic myeloid leukemia (CML) is a constitutively active BCR-ABL tyrosine kinase. Imatinib inhibits this… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine… (More)
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Highly Cited
1997
Highly Cited
1997
On the subject of acute myeloid leukemia (AML), there is little consensus about the target cell within the hematopoietic stem… (More)
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