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Myeloid Leukemia
Known as:
LEUKEMIA, GRANULOCYTIC, MALIGNANT
, Myelocytic Leukemias
, Unspecified myeloid leukemia
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A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are…
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National Institutes of Health
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Related topics
Related topics
48 relations
ABL2 gene
ABL2 wt Allele
ANXA8 gene
Acute Promyelocytic Leukemia
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Narrower (8)
Acute myelomonocytic leukemia
Eosinophilic leukemia
Granulocytic Sarcoma
Leukemia, Myelocytic, Acute
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Broader (3)
Neoplasm, uncertain whether benign or malignant
Neoplasms
leukemia
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Acute myeloid leukemia
Gert J. Ossenkoppele
Methods in Molecular Biology
2018
Corpus ID: 862665
Acute myeloid leukemia (AML) occurs with a frequency of 3.5/1,000,000/year cases. AML patients have an invasion of diseased cells…
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Highly Cited
2016
Highly Cited
2016
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
E. Papaemmanuil
,
M. Gerstung
,
+24 authors
P. Campbell
New England Journal of Medicine
2016
Corpus ID: 205099707
BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next…
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Highly Cited
2009
Highly Cited
2009
Recurring mutations found by sequencing an acute myeloid leukemia genome.
E. Mardis
,
L. Ding
,
+55 authors
T. Ley
New England Journal of Medicine
2009
Corpus ID: 25183214
BACKGROUND The full complement of DNA mutations that are responsible for the pathogenesis of acute myeloid leukemia (AML) is not…
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Highly Cited
2006
Highly Cited
2006
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia.
B. Druker
,
F. Guilhot
,
+29 authors
R. Larson
New England Journal of Medicine
2006
Corpus ID: 21772851
BACKGROUND The cause of chronic myeloid leukemia (CML) is a constitutively active BCR-ABL tyrosine kinase. Imatinib inhibits this…
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Highly Cited
2003
Highly Cited
2003
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
S. O’Brien
,
F. Guilhot
,
+22 authors
B. Druker
New England Journal of Medicine
2003
Corpus ID: 20464466
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic…
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Highly Cited
2003
Highly Cited
2003
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid…
B. Cheson
,
John M. Bennett
,
+17 authors
Clara D. Bloomfield
Journal of Clinical Oncology
2003
Corpus ID: 21628608
An International Working Group met to revise the diagnostic and response criteria for acute myelogenous leukemia originally…
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Highly Cited
2001
Highly Cited
2001
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
B. Druker
,
M. Talpaz
,
+8 authors
C. Sawyers
New England Journal of Medicine
2001
Corpus ID: 8399298
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine…
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Highly Cited
2001
Highly Cited
2001
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.
B. Druker
,
C. Sawyers
,
+5 authors
M. Talpaz
New England Journal of Medicine
2001
Corpus ID: 26116914
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is…
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Review
2000
Review
2000
The molecular biology of chronic myeloid leukemia.
M. Deininger
,
J. Goldman
,
J. Melo
Blood
2000
Corpus ID: 1044492
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph…
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Highly Cited
1997
Highly Cited
1997
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
D. Bonnet
,
J. Dick
Nature Network Boston
1997
Corpus ID: 205381050
On the subject of acute myeloid leukemia (AML), there is little consensus about the target cell within the hematopoietic stem…
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