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Myeloid Leukemia
Known as:
LEUKEMIA, GRANULOCYTIC, MALIGNANT
, Myelocytic Leukemias
, Unspecified myeloid leukemia
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A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are…
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National Institutes of Health
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Related topics
Related topics
48 relations
ABL2 gene
ABL2 wt Allele
ANXA8 gene
Acute Promyelocytic Leukemia
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Narrower (8)
Acute myelomonocytic leukemia
Eosinophilic leukemia
Granulocytic Sarcoma
Leukemia, Myelocytic, Acute
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Broader (3)
Neoplasm, uncertain whether benign or malignant
Neoplasms
leukemia
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
E. Papaemmanuil
,
M. Gerstung
,
+24 authors
P. Campbell
The New England journal of medicine
2016
Corpus ID: 205099707
BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next…
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Highly Cited
2013
Highly Cited
2013
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
T. Ley
,
Christopher B. Miller
,
+97 authors
G. Eley
The New England journal of medicine
2013
Corpus ID: 20280312
BACKGROUND Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships…
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Review
2010
Review
2010
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet.
H. Döhner
,
E. Estey
,
+16 authors
C. Bloomfield
Blood
2010
Corpus ID: 1088077
In 2003, an international working group last reported on recommendations for diagnosis, response assessment, and treatment…
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Highly Cited
2009
Highly Cited
2009
Recurring mutations found by sequencing an acute myeloid leukemia genome.
E. Mardis
,
L. Ding
,
+55 authors
T. Ley
The New England journal of medicine
2009
Corpus ID: 25183214
BACKGROUND The full complement of DNA mutations that are responsible for the pathogenesis of acute myeloid leukemia (AML) is not…
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Highly Cited
2006
Highly Cited
2006
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia.
B. Druker
,
F. Guilhot
,
+29 authors
R. Larson
The New England journal of medicine
2006
Corpus ID: 21772851
BACKGROUND The cause of chronic myeloid leukemia (CML) is a constitutively active BCR-ABL tyrosine kinase. Imatinib inhibits this…
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Highly Cited
2003
Highly Cited
2003
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
S. O’Brien
,
F. Guilhot
,
+22 authors
B. Druker
The New England journal of medicine
2003
Corpus ID: 20464466
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic…
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Review
2002
Review
2002
Acute myeloid leukemia.
F. Giles
,
A. Keating
,
A. Goldstone
,
I. Avivi
,
C. Willman
,
H. Kantarjian
Hematology. American Society of Hematology…
2002
Corpus ID: 862665
In this chapter, Drs. Keating and Willman review recent advances in our understanding of the pathophysiology of acute myeloid…
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Highly Cited
2001
Highly Cited
2001
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
B. Druker
,
M. Talpaz
,
+8 authors
C. Sawyers
The New England journal of medicine
2001
Corpus ID: 8399298
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine…
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Highly Cited
2001
Highly Cited
2001
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.
B. Druker
,
C. Sawyers
,
+5 authors
M. Talpaz
The New England journal of medicine
2001
Corpus ID: 26116914
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is…
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Highly Cited
1997
Highly Cited
1997
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
D. Bonnet
,
J. Dick
Nature Medicine
1997
Corpus ID: 205381050
On the subject of acute myeloid leukemia (AML), there is little consensus about the target cell within the hematopoietic stem…
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