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Multiple Myeloma

Known as: Myeloma Multiple, multiple myeloma (MM), multiple myelomatosis 
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones… 
National Institutes of Health

Related topics

Related topics

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100 ML zoledronic acid 0.05 MG/ML Injection5 ML zoledronic acid 0.8 MG/ML InjectionAldesleukinAtypical lymphocyte

Broader (1)

Neoplasms

Papers overview

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Highly Cited
1986
Highly Cited
1986
Mutational analysis of the immunoglobulin heavy chain promoter region.
Complete immunoglobulin heavy chain (IgH) genes (gamma and mu) containing the intronic IgH enhancer and mutations in the upstream… 
Highly Cited
1984
Highly Cited
1984
Human leukocyte interferon and intermittent high-dose melphalan-prednisone administration in the treatment of multiple myeloma: a randomized clinical trial from the Myeloma Group of Central Sweden.
In a randomized clinical trial intermittent high-dose melphalan/prednisone (MP) treatment has been compared with human leukocyte… 
Highly Cited
1980
Highly Cited
1980
Nodular glomerulopathy associated with nonamyloidotic kappa light chain deposits and excess immunoglobulin light chain synthesis.
A nodular glomerulopathy characterized by mesangial deposits of monoclonal kappa light chains was detected by immunofluorescence… 
Highly Cited
1979
Highly Cited
1979
Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine.
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to… 
Review
1977
Review
1977
Regulation of immunoglobulin expression in mouse myeloma cells.
Recent experimental evidence suggests that all the somatic cells of a given individual have considerable genetic potential and… 
1976
1976
Preparation of Fv fragment from the mouse myeloma XRPC-25 immunoglobulin possessing anti-dinitrophenyl activity.
The myeloma IgA protein produced by plasmacytoma XRPC-25, was isolated by affinity chromatography on dinitrophenyllysine… 
Highly Cited
1974
Highly Cited
1974
Variants of mouse myeloma cells that produce short immunoglobulin heavy chains.
After mutagenesis of cultured mouse myeloma cells with ICR 191 or Melphalan, variant clones were isolated that synthesized… 
1971
1971
Localization of two additional hypervariable regions in immunoglobulin heavy chains.
Cyanogen bromide fragments were isolated from the heavy chains of three human IgG myeloma proteins of the V(H)III subgroup… 
Highly Cited
1965
Highly Cited
1965
Humoral syndromes associated with cancer.
Summary Neoplasia of a tissue occasionally results in the production of a substance with hormonal activity similar to that… 
Highly Cited
1947
Highly Cited
1947
DISEASE
Background: Little is known about patients who frequently visit the emergency department (ED) for acute exacerbation of chronic…