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Mouse Model

The use of special strains of mice to study a human disease or condition, and how to prevent and treat it.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Additional file 8: of Phenotypic clustering: a novel method for microglial morphology analysis
Highly Cited
2015
Highly Cited
2015
Selective efficacy of zoledronic acid on metastasis in a patient‐derived orthotopic xenograph (PDOX) nude‐mouse model of human pancreatic cancer
Patient‐derived orthotopic xenograft (PDOX) nude‐mouse models replicate the behavior of clinical cancer, including metastasis… 
2008
2008
Applications of an Athymic Nude Mouse Model of Nonhealing Critical-Sized Calvarial Defects
Calvarial bone defects are a common clinical scenario in craniofacial surgery. Numerous approaches are used to reconstruct skull… 
Highly Cited
2005
Highly Cited
2005
PPARγ in endothelial cells influences high fat diet-induced hypertension
Highly Cited
2004
Highly Cited
2004
Brittle IV Mouse Model for Osteogenesis Imperfecta IV Demonstrates Postpubertal Adaptations to Improve Whole Bone Strength
The Brtl mouse model for type IV osteogenesis imperfecta improves its whole bone strength and stiffness between 2 and 6 months of… 
Highly Cited
2003
Highly Cited
2003
A Lymphatic Mechanism of Rotavirus Extraintestinal Spread in the Neonatal Mouse
ABSTRACT We used the neonatal mouse model of rotavirus infection and virus strains SA11-clone 4 (SA11-Cl4) and Rhesus rotavirus… 
Highly Cited
2002
Highly Cited
2002
Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis.
The adeno-associated viruses (AAV) offer new perspectives for cytokine gene transfer in rheumatoid arthritis (RA) because they… 
Highly Cited
2001
Highly Cited
2001
Homologous Collagen Substances for Vocal Fold Augmentation
Objectives/Hypothesis Dysphonia resulting from failure of glottic closure during voicing is a difficult clinical problem… 
Highly Cited
2000
Highly Cited
2000
Injury induces deficient interleukin-12 production, but interleukin-12 therapy after injury restores resistance to infection.
OBJECTIVE To assess at serial intervals the production of interleukin-12 (IL-12) by monocytes/macrophages from the peripheral… 
1985
1985
Cytotoxic effect of anti-Mr 67,000 protein immunotoxins on human tumors in a nude mouse model.
We have studied the potential use of immunotoxins (ITs) for therapeutic treatment of human tumors in an experimental model of… 
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