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Mouse Model

The use of special strains of mice to study a human disease or condition, and how to prevent and treat it.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Selective efficacy of zoledronic acid on metastasis in a patient‐derived orthotopic xenograph (PDOX) nude‐mouse model of human pancreatic cancer
Patient‐derived orthotopic xenograft (PDOX) nude‐mouse models replicate the behavior of clinical cancer, including metastasis… 
2014
2014
Synthetic studies on mitotic kinesin Eg5 inhibitors: synthesis and structure-activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives.
2009
2009
A bioluminescent orthotopic mouse model of human osteosarcoma that allows sensitive and rapid evaluation of new therapeutic agents In vivo.
Osteosarcoma (OSA) is the most common primary malignant bone tumor in children, 30% of whom develop lung metastases despite… 
2007
2007
A Human Monoclonal Immunoglobulin M Reduces Bacteremia and Inflammation in a Mouse Model of Systemic Pneumococcal Infection
ABSTRACT Antibody-based approaches to pneumococcal disease may hold promise for immunocompromised patients in whom vaccines are… 
2005
2005
An attenuated Salmonella Enteritidis strain derivative of the main genotype circulating in Uruguay is an effective vaccine for chickens.
2005
2005
Development of new injectable bulking agents: biocompatibility of radiopaque polymeric microspheres studied in a mouse model.
Radiopaque polymeric microspheres have a potential as new bulking agents for treatment of stress urinary incontinence (SUI). The… 
2002
2002
Isogenic mutants of the cag pathogenicity island of Helicobacter pylori in the mouse model of infection: effects on colonization efficiency.
Strains of Helicobacter pylori that contain the cag pathogenicity island (cag PAI) are associated with increased virulence and… 
Highly Cited
2001
Highly Cited
2001
Homologous Collagen Substances for Vocal Fold Augmentation
Objectives/Hypothesis Dysphonia resulting from failure of glottic closure during voicing is a difficult clinical problem… 
2001
2001
Evaluation of recombinant interleukin-2 immunotherapy for human hemangiosarcoma in a SCID mice model (WB-SCID).
1985
1985
Cytotoxic effect of anti-Mr 67,000 protein immunotoxins on human tumors in a nude mouse model.
We have studied the potential use of immunotoxins (ITs) for therapeutic treatment of human tumors in an experimental model of… 
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