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Mitotane

Known as: 2, 4'-Dichlorodiphenyldichloroethane, 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, Mitotanum 
A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (1)

Antineoplastic Agents, Hormonal

Narrower (3)

ChloditanChlodithanemitometh
Cushing SyndromeDrug AllergyIn BloodMitotane:MCnc:Pt:Ser/Plas:Qn

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
TRANS-3′-HYDROXYCOTININE O- AND N-GLUCURONIDATIONS IN HUMAN LIVER MICROSOMES
Trans-3′-hydroxycotinine is a major metabolite of nicotine in humans and is mainly excreted as O-glucuronide in smoker's urine… 
Highly Cited
1988
Highly Cited
1988
Clinical and hemodynamic comparison of VVI versus DDD pacing in patients with DDD pacemakers.
Highly Cited
1986
Highly Cited
1986
Evaluation by pulsed Doppler echocardiography of the atrial contribution to left ventricular filling in patients with DDD pacemakers.
Highly Cited
1986
Highly Cited
1986
What Is the Most Appropriate Stimulation Mode in Patients with Sinus Node Dysfunction?
Sinus node disease (SND) has caused many controversies about the appropriate stimulation mode. We compared the advantages and… 
Highly Cited
1984
Highly Cited
1984
Doppler ultrasound measurement of cardiac output in patients with physiologic pacemakers. Effects of left ventricular function and retrograde ventriculoatrial conduction.
Highly Cited
1978
Highly Cited
1978
Adhesion of chicken hepatocytes to polyacrylamide gels derivatized with N-acetylglucosamine.
Complex carbohydrates on the surfaces of eukaryotic cells are thought to participate in a wide variety of cell-cell interactions… 
Highly Cited
1975
Highly Cited
1975
Treatment of an adrenal cortical carcinoma with a combination of o,p′-DDD and aminoglutethimide
A patient with Cushing's syndrome due to an adrenocortical carcinoma is described. Treatment of residual disease and functional… 
Highly Cited
1973
Highly Cited
1973
Soyabean lipoxygenase: an iron-containing enzyme.
Highly Cited
1968
Highly Cited
1968
Inheritance of Susceptibility to Friend Mouse Leukemia Virus
Based on the previous observation that a single major autosomal gene controls susceptibility to Friend leukemia virus in mice, an… 
Highly Cited
1960
Highly Cited
1960
Studies on the enolization of pyruvate by pyruvate kinase.
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