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Mitotane

Known as: 2, 4'-Dichlorodiphenyldichloroethane, 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, Mitotanum 
A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Abstract Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine tumour deriving from the adrenal cortex. A correct… Expand
Review
2018
Review
2018
Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone producing tumor with variable prognosis. The purpose… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Adrenocortical carcinoma is a rare neoplasm characterized by a high risk of recurrence after radical resection… Expand
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Highly Cited
2007
Highly Cited
2007
  • S. Lehotay
  • Journal of AOAC International
  • 2007
  • Corpus ID: 27125868
A collaborative study was conducted to determine multiple pesticide residues in fruits and vegetables using a quick, simple… Expand
Highly Cited
2004
Highly Cited
2004
Background—Although dual-chamber pacing improves cardiac function in patients with complete congenital atrioventricular block… Expand
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Highly Cited
1998
Highly Cited
1998
There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES The aim of this study was to assess the potential acute benefit of multisite cardiac pacing with optimized… Expand
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Highly Cited
1994
Highly Cited
1994
Mitotane is considered to be the drug of choice for patients with inoperable, recurrent and metastatic adrenocortical carcinoma… Expand
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Highly Cited
1992
Highly Cited
1992
Mitral or tricuspid regurgitation of long duration may so shorten the ventricular filling time in dilated cardiomyopathy that… Expand
Highly Cited
1990
Highly Cited
1990
Adrenocortical carcinoma is a rare tumor, and only limited information is available about its natural history and the effects of… Expand