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Mitolactol

Known as: 6-dibromodideoxydulcitol, 6-dibromodulcitol, Dibromdicil 
A synthetic derivative of hexitol with antineoplastic and radiosensitizing properties. Mitolactol alkylates DNA via actual or derived epoxide groups… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (9)

1,2-anhydro-6-bromogalactitolADM protocolBVMM protocolDMV protocol

Broader (1)

Antineoplastic Agents, Alkylating
DAVTH protocolIn BloodNCIt Antineoplastic Agent Terminologyagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Increased Risk of Severe Recurrence of Hepatitis C Virus in Liver Transplant Recipients of Donation After Cardiac Death Allografts
Background. In hepatitis C virus (HCV) recipients of donation after cardiac death (DCD) grafts, there is suggestion of lower… 
2010
2010
Cascaded cross flow DBD-adsorbent technique for NOX abatement in diesel engine exhaust
In this paper, a different type of cross flow dielectric barrier discharge (DBD) reactor was designed and tested. Here the gas… 
2010
2010
Mesoporous TiO2 films fabricated using atmospheric pressure dielectric barrier discharge jet.
TiO2 nanoparticles were synthesized by a facile method of dielectric barrier discharge jet (DBD jet) for the dye-sensitized solar… 
Review
2008
Review
2008
Adjuvant dibromodulcitol and BCNU chemotherapy in anaplastic astrocytoma: results of a randomised European Organisation for Research and Treatment of Cancer phase III study (EORTC study 26882).
Review
1995
Review
1995
The platinum compounds and paclitaxel in the management of carcinomas of the endometrium and uterine cervix.
Endometrial carcinoma and squamous cell carcinoma of the cervix are common invasive neoplasms of the female genital tract. Early… 
Highly Cited
1993
Highly Cited
1993
Overproduction of the poly(ADP‐ribose) polymerase DNA‐binding domain blocks alkylation‐induced DNA repair synthesis in mammalian cells.
The zinc‐finger DNA‐binding domain (DBD) of poly (ADP‐ribose) polymerase (PARP, EC 2.4.2.30) specifically recognizes DNA strand… 
1992
1992
High performance liquid chromatography with chemiluminescence detection of methamphetamine and its related compounds using 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole.
A high performance liquid chromatographic assay of methamphetamine (MP) and its related compounds, i.e. ephedrine (EP… 
Highly Cited
1989
Highly Cited
1989
Fluorogenic reagent for thiols: 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole.
4-(N,N-Dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole (DBD-F) was synthesised for use as a more reactive, thiol-specific… 
Highly Cited
1986
Highly Cited
1986
Prospective evaluation of carcinoembryonic antigen levels and alternating chemotherapeutic regimens in metastatic breast cancer.
Ninety-seven eligible and evaluable women with metastatic breast cancer were placed on a prospective clinical protocol to… 
Highly Cited
1982
Highly Cited
1982
Dibromodulcitol and adriamycin +/- tamoxifen in advanced breast cancer.
The therapeutic effectiveness of combining tamoxifen with a combination chemotherapy regimen was tested in 135 patients with… 
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