Mitolactol

Known as: 6-dibromodideoxydulcitol, 6-dibromodulcitol, Dibromdicil 
A synthetic derivative of hexitol with antineoplastic and radiosensitizing properties. Mitolactol alkylates DNA via actual or derived epoxide groups… (More)

Topic mentions per year

Topic mentions per year

1956-2017
010020019562016

Papers overview

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Review
2016
Review
2016
Key factors contributing to early stages of atherosclerosis and plaque development include the pro-inflammatory cytokines… (More)
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Highly Cited
2014
Highly Cited
2014
Transcription factor (TF) DNA sequence preferences direct their regulatory activity, but are currently known for only ∼1% of… (More)
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Highly Cited
2008
Highly Cited
2008
DNA-binding domain (DBD) is a database of predicted sequence-specific DNA-binding transcription factors (TFs) for all publicly… (More)
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Highly Cited
2007
Highly Cited
2007
Summary form only given. Non-thermal plasmas are already well-known for their sterilization ability; however, the mechanisms of… (More)
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Highly Cited
2006
Highly Cited
2006
Prediction of the biological effect of missense substitutions has become important because they are often observed in known or… (More)
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Highly Cited
2005
Highly Cited
2005
The BRCA2 tumour suppressor is essential for the error-free repair of double-strand breaks (DSBs) in DNA by homologous… (More)
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Highly Cited
2003
Highly Cited
2003
Auxin response factors (ARFs) are transcription factors that bind to TGTCTC auxin response elements in promoters of early auxin… (More)
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Highly Cited
2003
Highly Cited
2003
Sperm DNA fragmentation is being increasingly recognized as an important cause of infertility. We herein describe the Sperm… (More)
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Highly Cited
1995
Highly Cited
1995
We find that tamoxifen is a potent activator of estrogen receptor (ER)- mediated induction of promoters regulated by AP-1 sites… (More)
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Highly Cited
1988
Highly Cited
1988
Extracts containing wild-type or mutant human estrogen receptor (ER) have been used to study the binding of ER to its responsive… (More)
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