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Mitogen-Activated Protein Kinase 13

Known as: p38delta, p38delta MAP Kinase, MAPK13 Mitogen Activated Protein Kinase 
A 38-kDa mitogen-activated protein kinase found expressed at high levels in LUNG; KIDNEY; TESTIS; PANCREAS; and SMALL INTESTINE. It may play a role… 
National Institutes of Health

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In BloodMAPK13 wt AlleleProcess of secretionantagonists & inhibitors

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MAPK13 protein, human

Papers overview

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2010
2010
THE P38&agr; AND P38&dgr; MAP KINASES MAY BE GENE THERAPY TARGETS IN THE FUTURE TREATMENT OF SEVERE BURNS
Microvascular barrier damage, induced by thermal injury, imposes life-threatening problems owing to the pathophysiological… 
2007
2007
Activation of PKCdelta and p38delta MAPK during okadaic acid dependent keratinocyte apoptosis.
There is substantial interest in identifying agents that differentially activate keratinocyte differentiation versus apoptosis… 
2006
2006
Induction of Apoptosis in Renal Cell Carcinoma by Reactive Oxygen Species: Involvement of Extracellular Signal-Regulated Kinase 1/2, p38δ/γ, Cyclooxygenase-2 Down-Regulation, and Translocation of…
Renal cell carcinoma (RCC) is the most common malignancy of the kidney. Unfortunately, RCCs are highly refractory to conventional… 
2006
2006
Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure.
PURPOSE To characterize the changes in retinal gene expression induced by elevated intraocular pressure (IOP) in a hereditary… 
2004
2004
The L1 retroelement-related p40 protein induces p38delta MAP kinase.
We characterized a full length L1 mRNA in a rheumatoid arthritis (RA) synovial tissue and determined the degree of methylation of… 
2003
2003
Phorbol Ester-dependent Activation of Peroxiredoxin I Gene Expression via a Protein Kinase C, Ras, p38 Mitogen-activated Protein Kinase Signaling Pathway*
The antioxidant protein peroxiredoxin (Prx) I is a thioredoxin peroxidase that is involved in the regulation of proliferation and… 
2002
2002
Potent transforming activity of the small GTP‐binding protein Rit in NIH 3T3 cells: evidence for a role of a p38γ‐dependent signaling pathway
1999
1999
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation.
The mechanism by which different mitogen activated protein kinases (MAPKs) distinguish between different substrates is poorly… 
1998
1998
Pervanadate inhibits mitogen‐activated protein kinase kinase‐1 in a p38MAPK‐dependent manner
1997
1997
Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).
Four mitogen-activated protein (MAP) kinase family members have been identifed in mammalian cells which are activated by cellular… 
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