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Mitochondrial Import Sequence

Known as: MTS, Mitochondrial Targeting Signal 
An amino acid sequence that directs the post-translational transport of a protein to the mitochondria. The sequence contains an alternating pattern… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Summary We have developed a method for rapidly inactivating proteins with rapamycin-induced heterodimerization. Cells were stably… Expand
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Highly Cited
2009
Highly Cited
2009
The synthesis and storage of neutral lipids in lipid droplets is a fundamental property of eukaryotic cells, but the spatial… Expand
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Highly Cited
2008
Highly Cited
2008
α-Synuclein, a protein implicated in the pathogenesis of Parkinson disease (PD), is thought to affect mitochondrial functions… Expand
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Highly Cited
2003
Highly Cited
2003
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the… Expand
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Highly Cited
2002
Highly Cited
2002
The SIR2 (silent information regulator 2) gene family has diverse functions in yeast including gene silencing, DNA repair, cell… Expand
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Highly Cited
2002
Highly Cited
2002
A T→G transversion at nt 8993 in mitochondrial DNA of MTATP6 (encoding ATPase 6 of complex V of the respiratory chain) causes… Expand
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Highly Cited
2000
Highly Cited
2000
Mitochondrial fission is mediated by the dynamin-related GTPase, Dnm1p, which assembles on the mitochondrial outer membrane into… Expand
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Highly Cited
1999
Highly Cited
1999
We identified seven alternatively spliced forms of human 8-oxoguanine DNA glycosylase (OGG1) mRNAs, classified into two types… Expand
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Highly Cited
1999
Highly Cited
1999
Ultrastructural analysis of Entamoeba histolytica reveals that this intestinal human pathogen lacks recognizable mitochondria… Expand
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Highly Cited
1995
Highly Cited
1995
Phospholipid-hydroperoxide glutathione peroxidase (PhGPx) is a selenoenzyme that reduces hydroperoxides of phospholipid… Expand
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