Mitochondrial Import Sequence

Known as: MTS, Mitochondrial Targeting Signal 
An amino acid sequence that directs the post-translational transport of a protein to the mitochondria. The sequence contains an alternating pattern… (More)
National Institutes of Health

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Glutaminase

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Highly Cited
2012
Highly Cited
2012
Mitochondrial ROMK channel is a molecular component of mitoK(ATP).
RATIONALE Activation of the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) has been implicated in the mechanism of… (More)
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Highly Cited
2010
Highly Cited
2010
The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.
The PB2 subunit of the influenza virus RNA polymerase is a major virulence determinant of influenza viruses. However, the… (More)
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Highly Cited
2008
Highly Cited
2008
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.
Alpha-synuclein, a protein implicated in the pathogenesis of Parkinson disease (PD), is thought to affect mitochondrial functions… (More)
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2005
2005
Functional and mutational characterization of human MIA40 acting during import into the mitochondrial intermembrane space.
A first component involved in import into the mitochondrial intermembrane space, named Mia40, has been described recently in… (More)
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2004
2004
Translation initiation from a naturally occurring non-AUG codon in Saccharomyces cerevisiae.
Although previous studies have already shown that both cytoplasmic and mitochondrial activities of glycyl-tRNA synthetase are… (More)
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Highly Cited
2003
Highly Cited
2003
Mitochondrial translocation of cofilin is an early step in apoptosis induction
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the… (More)
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Highly Cited
2002
Highly Cited
2002
Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus
A T→G transversion at nt 8993 in mitochondrial DNA of MTATP6 (encoding ATPase 6 of complex V of the respiratory chain) causes… (More)
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Highly Cited
2000
Highly Cited
2000
Mdv1p Is a Wd Repeat Protein That Interacts with the Dynamin-Related Gtpase, Dnm1p, to Trigger Mitochondrial Division
Mitochondrial fission is mediated by the dynamin-related GTPase, Dnm1p, which assembles on the mitochondrial outer membrane into… (More)
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Highly Cited
1997
Highly Cited
1997
Conservation of mitochondrial targeting sequence function in mitochondrial and hydrogenosomal proteins from the early-branching eukaryotes Crithidia, Trypanosoma and Trichomonas.
Kinetoplastid protozoa are the earliest-branching eukaryotes to possess a true mitochondrion. This organelle is host to a variety… (More)
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Highly Cited
1995
Highly Cited
1995
Peroxisomal and mitochondrial carnitine acetyltransferases of Saccharomyces cerevisiae are encoded by a single gene.
Carnitine acetyltransferase (CAT) is present in mitochondria and peroxisomes of oleate-grown Saccharomyces cerevisiae. Both… (More)
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