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Mitochondrial Import Sequence

Known as: MTS, Mitochondrial Targeting Signal 
An amino acid sequence that directs the post-translational transport of a protein to the mitochondria. The sequence contains an alternating pattern… Expand
National Institutes of Health

Related topics

Related topics

1 relation
Glutaminase

Papers overview

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Highly Cited
2010
Highly Cited
2010
Rapid Inactivation of Proteins by Rapamycin-Induced Rerouting to Mitochondria
Summary We have developed a method for rapidly inactivating proteins with rapamycin-induced heterodimerization. Cells were stably… Expand
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Highly Cited
2009
Highly Cited
2009
The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria*
The synthesis and storage of neutral lipids in lipid droplets is a fundamental property of eukaryotic cells, but the spatial… Expand
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Highly Cited
2008
Highly Cited
2008
Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain*
α-Synuclein, a protein implicated in the pathogenesis of Parkinson disease (PD), is thought to affect mitochondrial functions… Expand
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Highly Cited
2003
Highly Cited
2003
Mitochondrial translocation of cofilin is an early step in apoptosis induction
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the… Expand
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Highly Cited
2002
Highly Cited
2002
SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria
The SIR2 (silent information regulator 2) gene family has diverse functions in yeast including gene silencing, DNA repair, cell… Expand
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Highly Cited
2002
Highly Cited
2002
Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus
A T→G transversion at nt 8993 in mitochondrial DNA of MTATP6 (encoding ATPase 6 of complex V of the respiratory chain) causes… Expand
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Highly Cited
2000
Highly Cited
2000
Mdv1p Is a Wd Repeat Protein That Interacts with the Dynamin-Related Gtpase, Dnm1p, to Trigger Mitochondrial Division
Mitochondrial fission is mediated by the dynamin-related GTPase, Dnm1p, which assembles on the mitochondrial outer membrane into… Expand
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Highly Cited
1999
Highly Cited
1999
Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs.
We identified seven alternatively spliced forms of human 8-oxoguanine DNA glycosylase (OGG1) mRNAs, classified into two types… Expand
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Highly Cited
1999
Highly Cited
1999
The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica
Ultrastructural analysis of Entamoeba histolytica reveals that this intestinal human pathogen lacks recognizable mitochondria… Expand
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Highly Cited
1995
Highly Cited
1995
Rat Phospholipid-hydroperoxide Glutathione Peroxidase
Phospholipid-hydroperoxide glutathione peroxidase (PhGPx) is a selenoenzyme that reduces hydroperoxides of phospholipid… Expand
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