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Minocycline

Known as: (4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Minocyclin, 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,12aalpha))- 
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (18)

9-(N,N-dimethylglycylamido)minocyclineAkne-PurenAknin-MinoArestin
Acne VulgarisAnthrax diseaseHypersensitivityIn Blood

Broader (2)

Anti-Bacterial AgentsTetracycline Antibiotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Comparative in vitro antimicrobial susceptibilities and synergistic activities of antimicrobial combinations against carbapenem-resistant Acinetobacter species: Acinetobacter baumannii versus…
Highly Cited
2006
Highly Cited
2006
Evaluating therapeutic targets for reperfusion‐related brain hemorrhage
Early reperfusion after an ischemic stroke can cause blood–brain barrier injury with subsequent cerebral edema and devastating… 
Highly Cited
2005
Highly Cited
2005
Minocycline inhibits LPS-induced retinal microglia activation
Highly Cited
2004
Highly Cited
2004
Minocycline prevents cholinergic loss in a mouse model of Down's syndrome
Individuals with Down's syndrome develop Alzheimer's‐like pathologies comparatively early in life, including progressive… 
Highly Cited
2004
Highly Cited
2004
Benefits of minocycline and rifampin-impregnated central venous catheters
ObjectiveTo determine the efficacy of minocycline and rifampin-impregnated catheters compared to non-impregnated catheters in… 
Highly Cited
2004
Highly Cited
2004
Minocycline Exerts Multiple Inhibitory Effects on Vascular Endothelial Growth Factor–Induced Smooth Muscle Cell Migration: The Role of ERK1/2, PI3K, and Matrix Metalloproteinases
Widely used tetracycline antibiotics affect many cellular functions relevant to human vascular disease including cell… 
Highly Cited
1999
Highly Cited
1999
Methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci from conjunctivas of preoperative patients.
Highly Cited
1998
Highly Cited
1998
Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics. Application to discolored teeth.
Highly Cited
1992
Highly Cited
1992
Selective endothelial growth inhibition by tetracyclines that inhibit collagenase.
Highly Cited
1982
Highly Cited
1982
Hyperpigmentation associated with oral minocycline
Two patients receiving minocycline developed blue‐black pigmentation on the legs. Biopsies from the pigmented areas demonstrated… 
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