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Miniantibody

Known as: MiniAb 
A peptide resembling the complementary determining region of an antibody and retaining its specificity. These are being studied for therapeutic and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
A major goal in antibody design for cancer therapy is to tailor the pharmacokinetic properties of the molecule according to… Expand
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Highly Cited
2005
Highly Cited
2005
We monitored the number of intravascular platelet-leukocyte aggregates (PLAs) and thrombotic occlusions (TOs) by intravascular… Expand
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Highly Cited
2005
Highly Cited
2005
PEGylation is an attractive strategy to enhance the therapeutic efficacy of proteins with a short serum half-life. It can be used… Expand
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2001
2001
Multimerization of antibody fragments increases the valency and the molecular weight, both identified as key features in the… Expand
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Highly Cited
2001
Highly Cited
2001
The first version of the Human Combinatorial Antibody Library (HuCAL) is a single-chain Fv-based phage display library (HuCAL… Expand
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1998
1998
Bispecific antibodies extend the capabilities of nature and might be applied in immunotherapy and biotechnology. By fusing the… Expand
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1997
1997
A recombinant enzyme-linked immunosorbent assay (ELISA) system, entirely based on antibody fragments, is described here as an… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract Functional bivalent miniantibodies, directed against the epidermal growth factor receptor, accumulated to more than 3 gl… Expand
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1995
1995
We have designed tetravelent miniantibodies assembling in the periplasm of Escherichia coli. They are based on single-chain Fv… Expand
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1993
1993
The combination of single-chain Fv-fragments (scFv) with a C-terminal, flexible linking region followed by a designed or natural… Expand
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