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Miniantibody

Known as: MiniAb 
A peptide resembling the complementary determining region of an antibody and retaining its specificity. These are being studied for therapeutic and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
A major goal in antibody design for cancer therapy is to tailor the pharmacokinetic properties of the molecule according to… Expand
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Highly Cited
2005
Highly Cited
2005
We monitored the number of intravascular platelet-leukocyte aggregates (PLAs) and thrombotic occlusions (TOs) by intravascular… Expand
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Highly Cited
2005
Highly Cited
2005
PEGylation is an attractive strategy to enhance the therapeutic efficacy of proteins with a short serum half-life. It can be used… Expand
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Highly Cited
2001
Highly Cited
2001
Multimerization of antibody fragments increases the valency and the molecular weight, both identified as key features in the… Expand
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Highly Cited
2001
Highly Cited
2001
The first version of the Human Combinatorial Antibody Library (HuCAL) is a single-chain Fv-based phage display library (HuCAL… Expand
Highly Cited
1998
Highly Cited
1998
Bispecific antibodies extend the capabilities of nature and might be applied in immunotherapy and biotechnology. By fusing the… Expand
Highly Cited
1996
Highly Cited
1996
Abstract Functional bivalent miniantibodies, directed against the epidermal growth factor receptor, accumulated to more than 3 gl… Expand
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Highly Cited
1995
Highly Cited
1995
We have designed tetravelent miniantibodies assembling in the periplasm of Escherichia coli. They are based on single-chain Fv… Expand
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Highly Cited
1993
Highly Cited
1993
The combination of single-chain Fv-fragments (scFv) with a C-terminal, flexible linking region followed by a designed or natural… Expand
Highly Cited
1993
Highly Cited
1993
A complementarity-determining region (CDR) of the mouse monoclonal antibody (mAb) F58 was constructed with specificity to a… Expand
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