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A widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 in South and Central America and the Caribbean. A major… Expand In early 2015, an outbreak of Zika virus, a flavivirus transmitted by Aedes mosquitoes, was identified in northeast Brazil, an… Expand BACKGROUND
The incidence of microcephaly in Brazil in 2015 was 20 times higher than in previous years. Congenital microcephaly is… Expand BACKGROUND
The emergence of Zika virus in the Americas has coincided with increased reports of babies born with microcephaly. On… Expand An unexpected upsurge in diagnosis of fetal and pediatric microcephaly has been reported in the Brazilian press recently. Cases… Expand Due to the complexity of the human brain, it is difficult to study many brain disorders in model organisms, highlighting the need… Expand The complexity of the human brain has made it difficult to study many brain disorders in model organisms, highlighting the need… Expand Chromosome region 1q21.1 contains extensive and complex low-copy repeats, and copy number variants (CNVs) in this region have… Expand DNA double-strand breaks (DSBs) occur at random upon genotoxic stresses and represent obligatory intermediates during… Expand Rett syndrome (RTT, MIM 312750) is a progressive neurodevelopmental disorder and one of the most common causes of mental… Expand