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Mice, Transgenic

Known as: Transgenic mice, mouse transgenics, Mouse, Transgenic 
A mouse whose genome has been altered by the inclusion of foreign genetic material. The technique involves microinjection of foreign DNA fragments… 
National Institutes of Health

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Animals, Genetically ModifiedGenetic EngineeringIn BloodLaboratory mice

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Founder Mice, Transgenic

Papers overview

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Highly Cited
2012
Highly Cited
2012
Neuroprotective effects of progranulin in ischemic mice
Highly Cited
2001
Highly Cited
2001
Intergenic Transcription in the Human β-Globin Gene Cluster
ABSTRACT Our previous studies on nascent transcription across the human β-globin gene cluster revealed the presence of intergenic… 
Highly Cited
1999
Highly Cited
1999
Efficient selection of transgenic mouse embryos using EGFP as a marker gene
We have established a reliable method that uses the EGFP (Enhanced Green Fluorescent Protein) gene as a marker for selecting… 
Review
1999
Review
1999
Mechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis.
Studies of experimental autoimmune encephalomyelitis in conventional and transgenic mouse models have clarified mechanisms of… 
Highly Cited
1999
Highly Cited
1999
Hyperglycemia-induced embryonic dysmorphogenesis correlates with genomic DNA mutation frequency in vitro and in vivo.
Congenital malformations affecting multiple organ systems are at least three times more common in infants of mothers with IDDM… 
Highly Cited
1997
Highly Cited
1997
Multiple Pathways for the Initiation of T Helper 2 (Th2) Responses
Since the initial descriptions of CD4+ T cell subsets with distinct functions and cytokine production profiles, the question of… 
Review
1995
Review
1995
Transgenic mice and knockout mutants in the study of oxidative stress in brain injury.
A rapid increase in the need to explore the molecular basis of cellular function and injury in the central nervous system has led… 
Highly Cited
1993
Highly Cited
1993
Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene.
Photoreceptors of transgenic mice expressing a mutant rhodopsin gene (Pro347-->Ser) slowly degenerate. The mechanism of… 
Highly Cited
1993
Highly Cited
1993
Simple and efficient production of embryonic stem cell-embryo chimeras by coculture.
A method for the production of embryonic stem (ES) cell-embryo chimeras was developed that involves the simple coculture of eight… 
Highly Cited
1993
Highly Cited
1993
Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene.
A transgenic mouse line (TG.AC) created in the FVB/N strain, carries a v-Ha-ras gene fused to a zeta-globin promoter gene. These… 
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