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Mibefradil

Known as: (1S,2S)-(2-((3-(2-Benzimidazolyl)Propyl)Methylamino)Ethyl)-6-Fluoro-1,2,3,4-Tetrahydro-1-Isopropyl-2-Naphthyl Methoxyacetate, Acetic acid, methoxy-, 2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, (1S-cis)-, Mibefradil [Chemical/Ingredient] 
A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE.
National Institutes of Health

Related topics

Related topics

16 relations
Angina PectorisDecreased Blood Pressure [PE]Hypertensive diseaseIn Blood

Broader (3)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agents

Narrower (3)

Mibefradil DihydrochloridePosicorRo 40-5967

Papers overview

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2007
2007
Mibefradil-sensitive component involved in the plateau potential in submucosal interstitial cells of the murine proximal colon
2006
2006
The effect of mibefradil administered intrathecally and lateral ventricle to the pain threshold of the rats following chronic constriction injury(CCI) of the sciatic nerve
Aim To investigate the role of T type calcium channel of spinal cord and supraspinal on the pain threthold of the rats following… 
2006
2006
Title: Kappa Opioid Inhibition of Somatodendritic Dopamine Inhibitory Post-
Abstract In the midbrain, dopamine neurons can release dopamine somatodendritically. This results in an inhibitory post-synaptic… 
2000
2000
Left ventricular diastolic function and cardiac disease: a radionuclide angiography study
1999
1999
Effects of Verapamil and Mibefradil on Regional Blood Flow and Function in Normal and Ischemic Myocardium
Dear Sir, The value of the calcium antagonist verapamil in the treatment of coronary artery disease has been questioned… 
1998
1998
The withdrawal of mibefradil (Posicor)
1998
1998
Treatment of chronic angina pectoris with combination mibefradil and beta‐blocker therapy
Calcium antagonists (CAs) are often prescribed with beta blockers for patients with chronic stable angina who remain symptomatic… 
1998
1998
Effects of mibefradil
1995
1995
Hemolysis on Intravenous Administration of a New Calcium Antagonist
Hemolysis-inducing properties of the new calcium antagonist Ro 40–5967 administered intravenously to 39 healthy male subjects… 
1990
1990
In vivo and in vitro studies on drug metabolism and interactions involving mibefradil , isradipine , lidocaine , selegiline and metronidazole
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