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Methylnaltrexone bromide

Known as: naltrexone MB, morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, bromide, (5alpha,17R)-, N-methylnaltrexone bromide 
The bromide salt form of methylnaltrexone, a methyl derivative of noroxymorphone with selective, peripherally-acting mu-opioid receptor antagonistic… 
National Institutes of Health

Related topics

Related topics

6 relations
0.6 ML Methylnaltrexone bromide 20 MG/ML Injection0.6 ML Methylnaltrexone bromide 20 MG/ML Prefilled SyringeMethylnaltrexone bromide 150 MG Oral Tablet [Relistor]Quaternary Ammonium Compounds

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Relistor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Effects of methylnaltrexone in patients with narcotic bowel syndrome: a pilot observational study
Background:  Narcotic bowel syndrome (NBS) describes disabling chronic severe abdominal pain that worsens despite continuing or… 
2011
2011
Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness: A 3-Month Open-Label Treatment Extension Study
ABSTRACT Methylnaltrexone is a methylated form of the mu-opioid antagonist naltrexone that blocks peripheral effects of opioids… 
2010
2010
Methylnaltrexone bromide for the treatment of opioid‐induced constipation in patients with advanced illness – a cost‐effectiveness analysis
Aliment Pharmacol Ther 31, 911–921 
Review
2010
Review
2010
A Review of the Treatment of Opioid-induced Constipation with Methylnaltrexone Bromide
Objectives: Review and summarize the mechanism of action of methylnaltrexone bromide (methylnaltrexone) and its effectiveness in… 
1994
1994
Effect of a peripheral and a central acting opioid antagonist on the testicular response to stress in rats.
The possible involvement of opioid receptors in mediating the inhibitory effects of immobilization stress on testicular… 
1992
1992
Effects of the opiates on the paraventricular nucleus in genetically polydipsic mice
1989
1989
Endogenous opioid peptides in the control of food intake in cats
1987
1987
Role of peripheral and central opioid activity in analgesia induced by restraint stress.
1986
1986
Evidence for a central but not adrenal, opioid mediation in hypertension induced by brief isolation in the rat.
1985
1985
Central and peripheral involvement of mu receptors in gastric secretory effects of opioids in the dog.
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