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Methylglyoxal synthase

National Institutes of Health

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Carbon-Oxygen LyasesLyase

Papers overview

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2016
2016
An alternative allosteric pathway in thermophilic methylglyoxal synthase.
2015
2015
Establishing synthetic pathways in Escherichia coli for biosynthesis of C3 and C4 high value commodity chemicals
The rapid consumption of oil for fuel and chemicals is leading to carbon dioxide emission at vast quantities each year. At this… 
2004
2004
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change.
Two detailed mechanisms [Marks et al. (2001) Biochemistry 40, 6805] have been proposed to explain the activity of methylglyoxal… 
2004
2004
Mechanistic studies of leaving group effects on enzymatic catalysis by methylglyoxal synthase
This thesis describes the investigations of leaving group effects on enzymatic catalysis by Methylyoxal synthase (MGS). MGS is a… 
2002
2002
Functional specificities of methylglyoxal synthase and triosephosphate isomerase: a combined QM/MM analysis.
Combined SCC-DFTB/CHARMM calculations were carried out to analyze the origin for the functional specificities of triosephosphate… 
2001
2001
Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy.
Methylglyoxal synthase (MGS) and triosephosphate isomerase (TIM) share neither sequence nor structural similarities, yet the… 
2000
2000
Mirroring perfection: the structure of methylglyoxal synthase complexed with the competitive inhibitor 2-phosphoglycolate.
The crystal structure of the transition-state analogue 2-phosphoglycolate (2PG) bound to methylglyoxal synthase (MGS) is… 
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