Methyldigoxin

Pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, MW 1419) reversed congestive heart failure and various arrhythmias, influenced the NO… (More)

Digoxin, a drug of narrow therapeutic index, is a substrate for common transmembrane transporter, P-glycoprotein, encoded by… (More)

Recently, we found that potent P-glycoprotein (P-gp) inhibitors, such as verapamil and cyclosporin A, markedly modulated the… (More)

Methyldigoxin-12α-3H and the nonabsorbable marker polyethylene glycol (PEG) were administered orally to five healthy subjects… (More)

Digoxin and beta-methyldigoxin were evaluated pharmacokinetically in terms of P-glycoprotein (P-gp)-mediated drug interactions in… (More)

We investigated the specificity of obtained antisera to beta-methyldigoxin by the enzyme immunoassay. Three types of hapten… (More)

Glycoside concentrations in plasma and various tissues of dogs were determined after a single and repeated intravenous… (More)

The pharmacokinetics of intravenously administered solutions of 0.30-and 0.60-mg bolus doses of 3H-beta-methyldigoxin, labeled in… (More)

To obtain true half lives, glycoside elimination from six healthy subjects was studied for 14 days after multiple intravenous… (More)

In man the oral or intravenous administration of 4‴-methyldigoxin yields metabolites in urine which are soluble either in… (More)