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Methyl n-Butyl Ketone

Known as: Hexan 2 one, Methyl n-Butyl Ketone [Chemical/Ingredient], Hexan-2-one 
An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (5)

3-hydroxy-2-hexanone4,5-dihydroxy-2-hexanone4-hydroxymethyl isobutyl ketoneethyl-n-butyl ketone

Broader (1)

Hexanones
In BloodMethyl butyl ketone:MCnc:Pt:Bld:QnMethyl butyl ketone:MCnc:Pt:Urine:Qnagonists

Papers overview

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Highly Cited
2008
Highly Cited
2008
Asymmetric aza-Michael reactions of alpha,beta-unsaturated ketones with bifunctional organic catalysts.
Chiral amine motifs are ubiquitously presented in numerous biologically active and therapeutically important chiral molecules… 
Highly Cited
2003
Highly Cited
2003
1,2-Migration of the thio group in allenyl sulfides: efficient synthesis of 3-thio-substituted furans and pyrroles.
The 1,2-migration of the thio group is an important chemical transformation that is extensively used in carbohydrate chemistry… 
Highly Cited
2002
Highly Cited
2002
A chlorinated monoterpene ketone, acylated beta-sitosterol glycosides and a flavanone glycoside from Mentha longifolia (Lamiaceae).
Highly Cited
2002
Highly Cited
2002
Amine-catalyzed direct self Diels–Alder reactions of α,β-unsaturated ketones in water: synthesis of pro-chiral cyclohexanones
Highly Cited
2001
Highly Cited
2001
Ruthenium complex-catalyzed anti-Markovnikov hydration of terminal alkynes.
[reaction: see text]. Highly regioselective, efficient, and substituent-tolerant anti-Markovnikov hydration of terminal alkynes… 
Highly Cited
1999
Highly Cited
1999
Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia
Highly Cited
1987
Highly Cited
1987
Plant antitumor agents. 28. Resolution of a key tricyclic synthon, 5'(RS)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3' ,4'- f]delta 6,8-tetrahydro-indolizine: total synthesis and…
The resolution of the tricyclic ketone (3a + 3b) by the separation of diastereomeric adducts 4a and 4c of the precursor ketal 5… 
Highly Cited
1976
Highly Cited
1976
Toxicity and metabolism of methyl n-butyl ketone.
MEK (2-butanone) when combined with MBK (2-hexanone) markedly enhanced MBK neurotoxicity. MBK in rat plasma after exposure to MBK… 
Highly Cited
1975
Highly Cited
1975
Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone.
Chronic exposure of rats to 2,5-hexanedione (CH3COCH2CH2COCH3), a major metabolite of the neurotoxic industrial solvent methyl n… 
Highly Cited
1974
Highly Cited
1974
Toxic Polyneuropathy Produced by Methyl N-Butyl Ketone
A polyneuropathy affecting a large number of workers was recently observed at a plant producing plastic-coated and color-printed… 
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