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Methimazole

Known as: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-, Methimazole [Chemical/Ingredient], Merkazolil 
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (12)

1-methyl-3-propylimidazole-2-thioneDanantizolFavistanMercazol

Broader (1)

Antithyroid Agents
Decreased Protein Synthesis [PE]Drug AllergyGoiterImidazole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans.
Review
1991
Review
1991
Thyroid disease and pregnancy.
Highly Cited
1985
Highly Cited
1985
Catalytic activity and substrate specificity of the flavin-containing monooxygenase in microsomal systems: characterization of the hepatic, pulmonary and renal enzymes of the mouse, rabbit, and rat.
Highly Cited
1984
Highly Cited
1984
Methimazole pharmacology in the rat: studies using a newly developed radioimmunoassay for methimazole.
Methimazole [1-methyl-2-mercaptoimidazole (MMI)] was given to normal male rats in their drinking water in concentrations ranging… 
Highly Cited
1982
Highly Cited
1982
Mechanism of inactivation of thyroid peroxidase by thioureylene drugs.
Highly Cited
1982
Highly Cited
1982
Reactions of purified hog thyroid peroxidase with H2O2, tyrosine, and methylmercaptoimidazole (goitrogen) in comparison with bovine lactoperoxidase.
Highly Cited
1978
Highly Cited
1978
DRUG-INDUCED IMMUNOLOGICAL NEUTROPENIA
Highly Cited
1977
Highly Cited
1977
The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions.
Highly Cited
1974
Highly Cited
1974
S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase.
Highly Cited
1973
Highly Cited
1973
Effects of thyrotropin, prostaglandin E1 and iodide on cyclic 3',5'-AMP concentration in dog thyroid slices.
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