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Methimazole
Known as:
2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
, Methimazole [Chemical/Ingredient]
, Merkazolil
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A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl…
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National Institutes of Health
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Related topics
Related topics
34 relations
Narrower (12)
1-methyl-3-propylimidazole-2-thione
Danantizol
Favistan
Mercazol
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Broader (1)
Antithyroid Agents
Decreased Protein Synthesis [PE]
Drug Allergy
Goiter
Imidazole
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors
Thanigaimalai Pillaiyar
,
M. Manickam
,
V. Namasivayam
Journal of Enzyme Inhibition and Medicinal…
2017
Corpus ID: 19516155
Abstract Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye…
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Review
2015
Review
2015
Management of Graves Disease: A Review.
H. Burch
,
D. Cooper
JAMA
2015
Corpus ID: 205065482
IMPORTANCE Graves disease is the most common cause of persistent hyperthyroidism in adults. Approximately 3% of women and 0.5% of…
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Highly Cited
2010
Highly Cited
2010
Dissimilar hepatotoxicity profiles of propylthiouracil and methimazole in children.
S. Rivkees
,
A. Szarfman
Journal of Clinical Endocrinology and Metabolism
2010
Corpus ID: 37150965
BACKGROUND The antithyroid drugs propylthiouracil and methimazole were introduced for clinical use about 60 yr ago and are…
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Highly Cited
2007
Highly Cited
2007
Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease.
Hirotoshi Nakamura
,
J. Noh
,
K. Itoh
,
S. Fukata
,
A. Miyauchi
,
N. Hamada
Journal of Clinical Endocrinology and Metabolism
2007
Corpus ID: 9370184
CONTEXT Although methimazole (MMI) and propylthiouracil (PTU) have long been used to treat hyperthyroidism caused by Graves…
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Highly Cited
2003
Highly Cited
2003
Disappearance of humoral thyroid autoimmunity after complete removal of thyroid antigens
L. Chiovato
,
F. Latrofa
,
+8 authors
M. Marinò
Annals of Internal Medicine
2003
Corpus ID: 11225125
RiassuntoLe malattie autoimmuni della tiroide sono caratterizzate dalla presenza di anticorpi diretti contro la tireoperossidasi…
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Review
1999
Review
1999
Methimazole embryopathy: delineation of the phenotype.
M. Clementi
,
E. Di Gianantonio
,
E. Pelo
,
I. Mammi
,
R. Basile
,
R. Tenconi
American journal of medical genetics
1999
Corpus ID: 26127746
We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy…
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Review
1999
Review
1999
Warfarin Use among Ambulatory Patients with Nonvalvular Atrial Fibrillation: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
A. Go
,
E. Hylek
,
L. Borowsky
,
K. Phillips
,
J. Selby
,
D. Singer
Annals of Internal Medicine
1999
Corpus ID: 42074285
Atrial fibrillation is the most common, potent risk factor for ischemic stroke. Nonrheumatic atrial fibrillation, the predominant…
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Highly Cited
1998
Highly Cited
1998
Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy.
L. Bartalena
,
C. Marcocci
,
+10 authors
A. Pinchera
New England Journal of Medicine
1998
Corpus ID: 10828607
BACKGROUND The chief clinical characteristics of Graves' disease are hyperthyroidism and ophthalmopathy. The relation between the…
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Highly Cited
1996
Highly Cited
1996
Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha.
E. Roti
,
R. Minelli
,
+8 authors
L. Braverman
American Journal of Medicine
1996
Corpus ID: 30639632
Highly Cited
1980
Highly Cited
1980
Iodothyronine 5'-deiodinase from rat kidney: substrate specificity and the 5'-deiodination of reverse triiodothyronine.
J. L. Leonard
,
I. Rosenberg
Endocrinology
1980
Corpus ID: 7683447
Renal membranes (crude microsomal fraction) which catalyze the thiol-dependent outer ring deiodination of LT4 with the formation…
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