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Methimazole

Known as: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-, Methimazole [Chemical/Ingredient], Merkazolil 
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (12)

1-methyl-3-propylimidazole-2-thioneDanantizolFavistanMercazol

Broader (1)

Antithyroid Agents
Decreased Protein Synthesis [PE]Drug AllergyGoiterImidazole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II—The developmental pattern of neurons in relation to oxidative stress and…
Highly Cited
2010
Highly Cited
2010
Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: I. The development of the thyroid hormones–neurotransmitters and adenosinergic…
Highly Cited
2005
Highly Cited
2005
Effect of long-term continuous methimazole treatment of hyperthyroidism: comparison with radioiodine.
OBJECTIVE To investigate the long-term effects of continuous methimazole (MMI) therapy. DESIGN AND METHODS Five hundred and… 
Highly Cited
2001
Highly Cited
2001
Adverse effects of prenatal methimazole exposure.
BACKGROUND A specific phenotype of methimazole (MMI) induced malformations has recently been postulated. MMI embryopathy is… 
Review
1999
Review
1999
Methimazole embryopathy: delineation of the phenotype.
We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy… 
Highly Cited
1997
Highly Cited
1997
Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans.
Highly Cited
1997
Highly Cited
1997
Methimazole and propylthiouracil equally cross the perfused human term placental lobule.
Propylthiouracil (PTU) is widely believed to cross the placenta less freely than methimazole (MMI) and is therefore regarded as… 
Highly Cited
1984
Highly Cited
1984
Spectrophotometric assay of the flavin-containing monooxygenase and changes in its activity in female mouse liver with nutritional and diurnal conditions.
Highly Cited
1980
Highly Cited
1980
Iodothyronine 5'-deiodinase from rat kidney: substrate specificity and the 5'-deiodination of reverse triiodothyronine.
Renal membranes (crude microsomal fraction) which catalyze the thiol-dependent outer ring deiodination of LT4 with the formation… 
Highly Cited
1979
Highly Cited
1979
The liver microsomal FAD-containing monooxygenase. Spectral characterization and kinetic studies.
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