Methimazole

Known as: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-, Methimazole [Chemical/Ingredient], Merkazolil 
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
05010019482016

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The antithyroid drugs propylthiouracil and methimazole were introduced for clinical use about 60 yr ago and are… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Although methimazole (MMI) and propylthiouracil (PTU) have long been used to treat hyperthyroidism caused by Graves… (More)
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2007
2007
OBJECTIVE Patients with thyroid diseases have abnormalities of blood coagulation including an alteration of von Willebrand factor… (More)
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2001
2001
Hyperthyroidism is associated with a higher incidence of arterial thromboembolism; increasing age, atrial fibrillation, and… (More)
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2000
2000
Free radical-mediated oxidative stress has been implicated in the etiopathogenesis of several autoimmune disorders. We… (More)
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2000
2000
The purpose of this study was to investigate the effects of methimazole on renal function in cats with hyperthyroidism. Twelve… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The chief clinical characteristics of Graves' disease are hyperthyroidism and ophthalmopathy. The relation between the… (More)
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1995
1995
In mice given a single intraperitoneal injection of the antithyroid drug methimazole (0.44 mmol/kg; 50 mg/kg) detachment of the… (More)
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1988
1988
The efficacy and safety of the antithyroid drug methimazole were evaluated over a 3-year period in 262 cats with hyperthyroidism… (More)
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1977
1977
The placental transfer of 35S-labelled methimazole (MMI), carbimazole and propylthiouracil (PTU) has been examined in the rat in… (More)
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