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Methicillin Resistance

Known as: Resistance, Methicillin 
Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.
National Institutes of Health

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6 relations
MethicillinMethicillin SodiumMethicillin-ResistantMethicillin-Resistant Staphylococcus aureus

Papers overview

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Highly Cited
2000
Highly Cited
2000
In vivo deletion of the methicillin resistance mec region from the chromosome of Staphylococcus aureus strains.
Two sets of Staphylococcus aureus isolates recovered from two patients exhibited similar susceptibility profiles except for… 
Highly Cited
1994
Highly Cited
1994
Lack of mecA transcription in slime-negative phase variants of methicillin-resistant Staphylococcus epidermidis
Five phase variants (PV1 to PV5) of the well-characterized, slime-producing, methicillin-resistant, pathogenic strain of… 
Highly Cited
1990
Highly Cited
1990
Insertional inactivation of the mec gene in a transposon mutant of a methicillin-resistant clinical isolate of Staphylococcus aureus
All clinical strains of methicillin-resistant Staphylococcus aureus (MRSA) examined so far contain the mec gene and its product… 
Highly Cited
1988
Highly Cited
1988
The expression in Staphylococcus aureus of cloned DNA encoding methicillin resistance.
A 4 kb fragment of chromosomal DNA was cloned from a clinical strain of methicillin-resistant Staphylococcus aureus. It comprises… 
Highly Cited
1987
Highly Cited
1987
Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus
Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus is enhanced by 2 to 5% NaCl in the medium… 
Highly Cited
1981
Highly Cited
1981
The Prevalence of High-Level Methicillin Resistance in Multiply Resistant Hospital Staphylococci
This study was prompted by observing in the summer of 1975, five lethal septicemias caused by methicillin resistant staphylococci… 
Highly Cited
1973
Highly Cited
1973
Genetic analysis of methicillin-resistant strains of Staphylococcus aureus; evidence for their evolution from a single clone.
Summary Methicillin-resistant staphylococci are characterised by: (a) chromosomal resistance to streptomycin, (b) tetracycline… 
Highly Cited
1972
Highly Cited
1972
Genetic control in methicillin-resistant strains of Staphylococcus aureus.
Summary Six methicillin-resistant strains of Staphylococcus aureus isolated in Britain were examined for loss of resistance after… 
Highly Cited
1972
Highly Cited
1972
Suppression of Intrinsic Resistance to Methicillin and Other Penicillins in Staphylococcus aureus
The pH of the medium in which staphylococcal susceptibility to penicillins was determined was found to make a profound difference… 
Highly Cited
1969
Highly Cited
1969
Extrachromosomal Control of Methicillin Resistance and Toxin Production in Staphylococcus aureus
All of 41 naturally occurring coagulase-positive methicillin-resistant strains of Staphylococcus aureus isolated in various… 
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