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Mefruside

Known as: 1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-((tetrahydro-2-methyl-2-furanyl)methyl)-, Mefruside [Chemical/Ingredient] 
A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

Diuretics
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

mefruside lactone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Enantioselective deprotonative ring contraction of N1-methyl-N4-Boc-benzo[e][1,4]diazepine-2,5-diones.
N1-Methyl-N4-Boc-benzo[e][1,4]diazepine-2,5-diones were prepared in good yield and high stereochemical purity from five amino… 
2012
2012
On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library. 3. Focus on ion trap and upfront CID.
Mass spectral libraries represent versatile tools for the identification of small bioorganic molecules. Libraries based on… 
2009
2009
Blood pressure reduction and vascular adaptation. A study on long-term effects of treatment with mefruside or atenolol.
Systemic BP reduction, calf blood flow and vascular resistance in the calf were determined in forty-two previously untreated… 
2009
2009
The effect of mefruside on plasma and muscle electrolytes and blood pressure in normal subjects and in patients with essential hypertension.
. The effect of mefruside on plasma and muscle electrolytes has been studied in 10 normal subjects and in 8 patients with… 
2009
2009
Haemodynamic effects of four months' mefruside therapy in hypertensive patients.
The haemodynamic changes after 4 months' mefruside therapy in 13 patients with essential hypertension have been studied… 
Highly Cited
1997
Highly Cited
1997
Rapid induction of apoptosis by deregulated uptake of polyamine analogues.
Treatment of Chinese hamster ovary cells with alpha-difluoromethylornithine for 3 days, followed by exposure to cycloheximide… 
1987
1987
Liquid chromatographic screening of diuretics in urine.
Highly Cited
1985
Highly Cited
1985
Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role.
1980
1980
An evaluation of debrisoquine and mefruside in the treatment of hypertension in African and Indian patients.
A double-blind, crossover trial was carried out in 20 hypertensive patients (9 African and 11 Indian) to compare the… 
1977
1977
[Correlations between blood pressure, blood volume and plasma renin during therapy with diuretics in essential hypertension. Comparison between the mineralocorticoid antagonist spironolactone and the…
35 patients with benign essential hypertension were treated for 6 weeks with high doses of the mineralocorticoid-antagonist… 
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