Medical Castration

Refers to the use of drugs to suppress the function of the ovaries or testicles.
National Institutes of Health

Papers overview

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2013
2013
BACKGROUND We seek to determine if testosterone levels below the accepted castration threshold (50 ng/dL) have an impact on time… (More)
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Highly Cited
2007
Highly Cited
2007
Androgen deprivation therapy (ADT) remains the primary treatment for advanced prostate cancer. The efficacy of ADT has not been… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT The impact of serum androgen manipulation on prostate tissue hormone levels in normal men is unknown. Studies of men with… (More)
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Review
2004
Review
2004
The categorization of prostate cancers that are progressing after castration as 'hormone-refractory' evolved from the clinical… (More)
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2003
2003
The goal of this study was to investigate the effects of medical castration (luteinizing hormone-receptor hormone [LH-RH] agonist… (More)
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Highly Cited
2003
Highly Cited
2003
Most prostate cancers (PCs) become resistant to combined androgen blockade therapy with surgical or medical castration and… (More)
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Highly Cited
2000
Highly Cited
2000
The present study was undertaken to evaluate the prognostic significance of the serum levels of interleukin 6 (IL-6) in patients… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Surgical or medical castration and antiestrogenic treatment with tamoxifen are common endocrine treatments for… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES To evaluate the efficacy and tolerability of 'Casodex' monotherapy (150 mg daily) for metastatic and locally advanced… (More)
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Review
1994
Review
1994
The use of agonistic analogues of luteinizing hormone releasing hormone (LHRH) is an established therapy for hormone-dependent… (More)
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