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Medetomidine

Known as: IH-Imidazole, 4(1-(2,3-dimethylphenyl)ethyl)-, Levomedetomidine, Medetomidine [Chemical/Ingredient] 
An agonist of RECEPTORS, ADRENERGIC ALPHA-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

Adrenergic alpha-2 Receptor AgonistsAnalgesics, Non-NarcoticHypnotics and Sedatives
DexmedetomidineIn Bloodagonistsanalogs & derivatives

Narrower (2)

MPV-785Medetomidine Hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
High field BOLD response to forepaw stimulation in the mouse
Highly Cited
2006
Highly Cited
2006
A fully noninvasive and robust experimental protocol for longitudinal fMRI studies in the rat
Review
2004
Review
2004
Pain management in cats—past, present and future. Part 2. Treatment of pain—clinical pharmacology
Review
1999
Review
1999
Propofol anesthesia.
Highly Cited
1997
Highly Cited
1997
The comparative hypoxaemic effect of four alpha 2 adrenoceptor agonists (xylazine, romifidine, detomidine and medetomidine) in sheep.
In the present study, the hypoxaemic potential of four alpha 2 agonists possessing different selectivity for alpha 2… 
Highly Cited
1990
Highly Cited
1990
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy.
The antinociceptive interaction on the tail flick (TF) and hot plate (HP) tests between opioid analgesics and medetomidine after… 
Review
1989
Review
1989
Pharmacological profiles of medetomidine and its antagonist, atipamezole.
Medetomidine, (+/-)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, is a very potent, selective and specific full agonist at both… 
Review
1989
Review
1989
Introduction to the clinical pharmacology of medetomidine.
Medetomidine is a sedative and analgesic drug intended for use in dogs and cats but it can also be successfully used in many… 
Highly Cited
1989
Highly Cited
1989
Sedative and analgesic effects of medetomidine in dogs.
The sedative and analgesic effects of medetomidine were studied in 18 laboratory beagles in a randomized cross-over study which… 
Highly Cited
1989
Highly Cited
1989
Medetomidine, a new sedative-analgesic for use in the dog and its reversal with atipamezole
The sedative and physiological effects of intramuscular medetomidine (20 and 40 μg/kg) in dogs were compared with those of… 
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