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MaxiPost

 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The catalytic enantioselective fluorination of N-H-free 3-substituted oxindoles was accomplished by a Sc(III)/N,N'-dioxide… Expand
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Highly Cited
2012
Highly Cited
2012
The indole ring is present in many pharmaceutically active compounds, as in MaxiPost™ (or BMS-204352), an active pharmaceutical… Expand
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2011
2011
Currently, there are no effective pharmacological therapies for chronic tinnitus despite a number of efforts from clinical… Expand
Highly Cited
2005
Highly Cited
2005
Neuronal Kv7 channels are recognized as potential drug targets for treating hyperexcitability disorders such as pain, epilepsy… Expand
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2005
2005
MaxiPost [(3S)-(+)-(5-chloro-2-methoxyphenyl)-1,3-dihydro-3-fluoro-6-(trifluoromethyl)-2H-indole-2-one); BMS-204352] is an… Expand
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2004
2004
MaxiPost [(3S)-(+)-(5-chloro-2-methoxyphenyl)-1,3-dihydro-3-fluoro-6-(trifluoromethyl)-2H-indole-2-one), or BMS-204352)] is a… Expand
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Highly Cited
2003
Highly Cited
2003
We have employed a cinchona alkaloid/Selectfluor-mediated enantioselective fluorination of the oxindole 2 to achieve the first… Expand
2003
2003
The enantioselective synthesis of a potent Maxi-K potassium channel opener (BMS-204352) mediated by N-fluoroammonium salts of… Expand
2003
2003
(3S)-(+)-(5-Chloro-2-methoxyphenyl)-1,3-dihydro-3-fluoro-6-(trifluoromethyl)-2H-indole-2-one) (MaxiPost, BMS-204352) is a potent… Expand
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Highly Cited
2002
Highly Cited
2002
3-Aryl-3-fluorooxindoles can be efficiently synthesized in two steps by the addition of an aryl Grignard to an isatin, followed… Expand