Matrix Metalloproteinase 2

Known as: 72kDa Gelatinase, Matrix Metalloproteinase-2, 72-kDa Type IV Collagenase 
72 kDa type IV collagenase (660 aa, ~74 kDa) is encoded by the human MMP2 gene. This protein is involved in both proteolysis and angiogenesis.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
UNLABELLED Hepatocellular carcinoma (HCC) is a highly vascularized tumor with frequent intrahepatic metastasis. Active… (More)
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Highly Cited
2004
Highly Cited
2004
The expression of matrix metalloproteinase-2 (MMP-2) has been linked with tumor invasion, angiogenesis, and metastasis. However… (More)
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Highly Cited
2003
Highly Cited
2003
Primary brain tumors (gliomas) have the unusual ability to diffusely infiltrate the normal brain thereby evading surgical… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Matrix metalloproteinases are best recognized for their ability to degrade the extracellular matrix in both… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To develop an optical imaging method to determine the expression level of tumoral matrix metalloproteinase-2 (MMP-2) in… (More)
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Highly Cited
1999
Highly Cited
1999
To assess whether the progression of plasma cell tumors is accompanied by angiogenesis and secretion of matrix-degrading enzymes… (More)
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Highly Cited
1999
Highly Cited
1999
Matrix metalloproteinases (MMPs) catalyze extracellular matrix degradation. Control of their activity is a promising target for… (More)
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Highly Cited
1997
Highly Cited
1997
Structural changes in the extracellular matrix are necessary for cell migration during tissue remodeling and tumor invasion… (More)
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Highly Cited
1997
Highly Cited
1997
The beta-amyloid peptide, which forms extracellular cerebral deposits in Alzheimer's disease, is derived from a large membrane… (More)
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Highly Cited
1995
Highly Cited
1995
The 72-kDa gelatinase/type IV collagenase (MMP-2) is a member of the matrix metalloproteinase (MMP) family of enzymes. This… (More)
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