Matrilin Proteins

Known as: Matrilins, Matrix Proteins, Cartilage, Proteins, Matrilin 
PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC… (More)
National Institutes of Health

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In BloodMATN1 geneProcess of secretionagonists
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MATN1 protein, humanMATN2 protein, humanMatn1 protein, mouseMatrilin-2
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Papers overview

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2009
2009
The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration.
Matrilins are adaptor proteins of the extracellular matrix involved in the formation of both collagen-dependent and collagen… (More)
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2007
2007
Cyclic equibiaxial tensile strain induces both anabolic and catabolic responses in articular chondrocytes.
Mechanical disturbance is directly implicated in the development of osteoarthritis (OA) but the precise mode for degenerative… (More)
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Highly Cited
2006
Highly Cited
2006
Effects of hydrostatic pressure and transforming growth factor-beta 3 on adult human mesenchymal stem cell chondrogenesis in vitro.
This study examined the effects of intermittent hydrostatic pressure (IHP) and transforming growth factor-beta 3 on… (More)
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Highly Cited
2004
Highly Cited
2004
Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.
The cartilage oligomeric matrix protein (COMP) and matrilins are abundant non-collagenous proteins in the cartilage extracellular… (More)
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2004
2004
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.
Matrilins are putative adaptor proteins of the extracellular matrix (ECM) which can form both collagen-dependent and collagen… (More)
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Highly Cited
2003
Highly Cited
2003
Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.
Beta1 integrins are highly expressed on chondrocytes, where they mediate adhesion to cartilage matrix proteins. To assess the… (More)
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Review
2002
Review
2002
Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.
The von Willebrand A (VWA) domain is a well-studied domain involved in cell adhesion, in extracellular matrix proteins, and in… (More)
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2000
2000
Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta.
OBJECTIVE To develop a reproducible immortalized human chondrocyte culture model for studying the regulation of chondrocyte… (More)
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Review
1999
Review
1999
The matrilins: a novel family of oligomeric extracellular matrix proteins.
The matrilin family at present has four members that all share a structure made up of von Willebrand factor A domains, epidermal… (More)
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Highly Cited
1993
Highly Cited
1993
TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases.
Using an in vitro model of rat epiphyseal chondrocyte differentiation in which cells are maintained in a three-dimensional cell… (More)
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