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Mastocytosis

Known as: cell disorders mast, cell diseases mast, Mast Cell Disease 
A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ… Expand
National Institutes of Health

Related topics

Related topics

26 relations
Blood supply aspectsBone MarrowBone marrow stem cellCromolyn
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Narrower (3)

Mastocytic enterocolitisMastocytosis, Diffuse CutaneousUrticaria Pigmentosa

Broader (1)

manifestations of immunopathology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations.
Adult mastocytosis is an incurable clonal disease associated with c-KIT mutations, mostly in exon 17 (D816V). In contrast… Expand
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Highly Cited
2009
Highly Cited
2009
Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates
TET2 (TET oncogene family member 2) is a candidate tumor suppressor gene located at chromosome 4q24, and was recently reported to… Expand
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Review
2008
Review
2008
Mast cells and mastocytosis.
Mast cells have been recognized for well over 100 years. With time, human mast cells have been documented to originate from CD34… Expand
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Review
2007
Review
2007
Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.
Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for… Expand
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Highly Cited
2007
Highly Cited
2007
Prevalence of allergy and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a study of the Spanish network on mastocytosis (REMA).
BACKGROUND Mast cells (MCs) play a key role in allergic diseases through the release of inflammatory mediators, which are… Expand
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Highly Cited
2006
Highly Cited
2006
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.
Eosinophilic esophagitis (EE) is an emerging disorder with a poorly understood pathogenesis. In order to define disease… Expand
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Highly Cited
2005
Highly Cited
2005
Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders.
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the importance of aberrant… Expand
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Highly Cited
2004
Highly Cited
2004
A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib.
Mutational analysis of the c-kit gene in a patient with a previously undescribed variant of mast cell disease revealed a germline… Expand
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Highly Cited
1987
Highly Cited
1987
Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis.
Better methods are needed to assess mast-cell activation in vivo and to distinguish the activation of mast cells from that of… Expand
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Highly Cited
1968
Highly Cited
1968
Textbook of dermatology
Epidemiology and historical bibliography comparative dermatology anatomy and organization of human skin functions of the skin… Expand
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