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Mannose-Binding Protein-Associated Serine Proteases

Known as: MBP Associated Serine Protease, Mannose-Binding Protein-Associated Serine Protease, Serine Protease, MBP-Associated 
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also… Expand
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

Immunologic Factors

Narrower (3)

MASP-1 protein, ratMASP-2 protein, ratMASP1 protein, human
MASP-Related ProteinMASP1 geneProcess of secretionantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Two Mechanisms for Mannose-binding Protein Modulation of the Activity of Its Associated Serine Proteases*
Serum mannose-binding protein (MBP) neutralizes invading microorganisms by binding to cell surface carbohydrates and activating… Expand
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Review
2004
Review
2004
The lectin‐complement pathway – its role in innate immunity and evolution
Summary:  Innate immunity was formerly thought to be a non‐specific immune response characterized by phagocytosis. However… Expand
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Highly Cited
2003
Highly Cited
2003
Crystal structure of the CUB1‐EGF‐CUB2 region of mannose‐binding protein associated serine protease‐2
Serum mannose‐binding proteins (MBPs) are C‐type lectins that recognize cell surface carbohydrate structures on pathogens, and… Expand
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Highly Cited
2002
Highly Cited
2002
Enhancement of Complement Activation and Opsonophagocytosis by Complexes of Mannose-Binding Lectin with Mannose-Binding Lectin-Associated Serine Protease After Binding to Staphylococcus aureus1
Human mannose-binding lectin (MBL) is a serum protein of the innate immune system that circulates as a complex with a group of so… Expand
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Review
2002
Review
2002
The biological functions of MBL-associated serine proteases (MASPs).
The Mannose-binding lectin-associated serine proteases (MASPs) have been the subject of intensive research particularly over the… Expand
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Highly Cited
2001
Highly Cited
2001
MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway.
The mannan-binding lectin (MBL) pathway of complement activation is part of the innate immune defense. The binding of MBL to… Expand
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Highly Cited
2001
Highly Cited
2001
Stoichiometry of Complexes between Mannose-binding Protein and Its Associated Serine Proteases
Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of… Expand
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Highly Cited
2000
Highly Cited
2000
Cutting Edge: Complement-Activating Complex of Ficolin and Mannose-Binding Lectin-Associated Serine Protease1
Both ficolins and mannose-binding lectin (MBL) are lectins characterized by the presence of collagen-like and carbohydrate… Expand
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Highly Cited
2000
Highly Cited
2000
Proteolytic Activities of Two Types of Mannose-Binding Lectin-Associated Serine Protease
Mannose (or mannan)-binding lectin (MBL) is an oligomeric serum lectin that plays a role in innate immunity by activating the… Expand
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Highly Cited
2000
Highly Cited
2000
Interaction of Mannose-binding Protein with Associated Serine Proteases
Mannose-binding protein (MBP; mannose-binding lectin) forms part of the innate immune system. By binding directly to… Expand
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