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Mannose-Binding Protein-Associated Serine Proteases

Known as: MBP Associated Serine Protease, Mannose-Binding Protein-Associated Serine Protease, Serine Protease, MBP-Associated 
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

Immunologic Factors

Narrower (3)

MASP-1 protein, ratMASP-2 protein, ratMASP1 protein, human
MASP-Related ProteinMASP1 geneProcess of secretionantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Therapeutic role for mannose-binding lectin in cigarette smoke-induced lung inflammation? Evidence from a murine model.
Defective efferocytosis in the airway may perpetuate inflammation in smokers with/without chronic obstructive pulmonary disease… 
2006
2006
Cloning and Characterization of Mannose-Binding Lectin from Lamprey (Agnathans)12
The recognition of pathogens is mediated by a set of pattern recognition molecules that recognize conserved pathogen-associated… 
Highly Cited
2003
Highly Cited
2003
Crystal structure of the CUB1‐EGF‐CUB2 region of mannose‐binding protein associated serine protease‐2
Serum mannose‐binding proteins (MBPs) are C‐type lectins that recognize cell surface carbohydrate structures on pathogens, and… 
Highly Cited
2002
Highly Cited
2002
Characterization of the Interaction Between L-Ficolin/P35 and Mannan-Binding Lectin-Associated Serine Proteases-1 and -21
Ficolins are oligomeric lectins comprising a collagen-like and a fibrinogen-like domain, with a binding specificity for N… 
Highly Cited
2001
Highly Cited
2001
Stoichiometry of Complexes between Mannose-binding Protein and Its Associated Serine Proteases
Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of… 
Review
2001
Review
2001
Structure and function of complement activating enzyme complexes: C1 and MBL-MASPs.
The complement system is a major effector arm of the immune defense contributing to the destruction of invading pathogens. There… 
2000
2000
A novel truncated isoform of the mannose-binding lectin-associated serine protease (MASP) from the common carp (Cyprinus carpio)
Abstract The mannose-binding lectin (MBL) and MBL-associated serine proteases (MASPs) play crucial roles in activation of the… 
Highly Cited
1999
Highly Cited
1999
Opsonic complement system of the solitary ascidian, Halocynthia roretzi.
Review
1998
Review
1998
MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway.
Highly Cited
1995
Highly Cited
1995
The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.
The human mannose-binding protein (MBP) is a pattern recognition molecule that appears to play a role in initial host defence… 
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