Mannose-Binding Protein-Associated Serine Proteases

Known as: MBP Associated Serine Protease, Mannose-Binding Protein-Associated Serine Protease, Serine Protease, MBP-Associated 
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also… (More)
National Institutes of Health

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Broader (1)

Immunologic Factors
MASP-Related ProteinMASP1 geneProcess of secretionantagonists & inhibitors
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Narrower (1)

MASP1 protein, human

Papers overview

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Review
2007
Review
2007
Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins.
Mannan-binding lectin (MBL), L-ficolin, M-ficolin and H-ficolin are all complement activating soluble pattern recognition… (More)
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Review
2005
Review
2005
Mannan-binding-lectin-associated serine proteases, characteristics and disease associations
Mannan-binding lectin (MBL)-associated serine proteases (MASPs) circulate in plasma as zymogens in complexes with MBL and with L… (More)
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Highly Cited
2004
Highly Cited
2004
Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases.
Serum mannose-binding protein (MBP) neutralizes invading microorganisms by binding to cell surface carbohydrates and activating… (More)
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Review
2003
Review
2003
Anti-microbial activities of mannose-binding lectin.
Mannose-binding lectin (MBL; also known as mannan-binding lectin) is involved in first-line defence by binding to bacteria… (More)
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2003
2003
Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2.
Serum mannose-binding proteins (MBPs) are C-type lectins that recognize cell surface carbohydrate structures on pathogens, and… (More)
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Review
2002
Review
2002
The biological functions of MBL-associated serine proteases (MASPs).
The Mannose-binding lectin-associated serine proteases (MASPs) have been the subject of intensive research particularly over the… (More)
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Highly Cited
2002
Highly Cited
2002
Enhancement of complement activation and opsonophagocytosis by complexes of mannose-binding lectin with mannose-binding lectin-associated serine protease after binding to Staphylococcus aureus.
Human mannose-binding lectin (MBL) is a serum protein of the innate immune system that circulates as a complex with a group of so… (More)
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Highly Cited
2000
Highly Cited
2000
Cutting edge: complement-activating complex of ficolin and mannose-binding lectin-associated serine protease.
Both ficolins and mannose-binding lectin (MBL) are lectins characterized by the presence of collagen-like and carbohydrate… (More)
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Highly Cited
2000
Highly Cited
2000
Proteolytic activities of two types of mannose-binding lectin-associated serine protease.
Mannose (or mannan)-binding lectin (MBL) is an oligomeric serum lectin that plays a role in innate immunity by activating the… (More)
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2000
2000
Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations.
Mannose-binding protein (MBP; mannose-binding lectin) forms part of the innate immune system. By binding directly to… (More)
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