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Major histocompatibility complex gene

Known as: HLA Complex Gene, MHC gene 
A group of linked loci, collectively termed H-2 complex in the mouse and HLA complex in humans, that codes for cell-surface histocompatibility… Expand
National Institutes of Health

Related topics

Related topics

2 relations
Antigen PresentationImmunoregulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Evolution of major histocompatibility complex gene copy number
MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show… Expand
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2006
2006
Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases
The telomeric class III region of the major histocompatibility complex is gene dense, but apart from the three tumour necrosis… Expand
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2002
2002
Baboon placentas express soluble and membrane-bound Paan-AG proteins encoded by alternatively spliced transcripts of the class Ib major histocompatibility complex gene, Paan-AG
Abstract. The human class Ib major histocompatibility complex (MHC) molecule, HLA-G, is unique in its limited polymorphism, high… Expand
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Highly Cited
2000
Highly Cited
2000
CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis.
BACKGROUND/AIM Primary biliary cirrhosis (PBC) is an autoimmune cholestatic liver disease thought to develop through a complex… Expand
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1999
1999
Repression of major histocompatibility complex genes by a human trophoblast ribonucleic acid.
The suppression of polymorphic major histocompatibility complex antigen expression in human trophoblasts is critical for the… Expand
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Highly Cited
1997
Highly Cited
1997
Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation of multiple regions of the TATA box binding protein.
CIITA is a positive regulator of class II major histocompatibility complex gene transcription that has been found to be defective… Expand
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1992
1992
Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis.
Autoimmune vasculitis represents a disease characterized by focal inflammation within arteries at multiple sites in the… Expand
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1988
1988
Identification of negative and positive regulatory elements associated with a class I major histocompatibility complex gene.
Regulatory DNA sequence elements were functionally identified in the 5'-flanking region of a gene, PD1, which encodes a porcine… Expand
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1987
1987
Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.
We have used in vitro deletion mutagenesis in combination with DNA transfection to search for cis-acting regulatory elements… Expand
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1984
1984
Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.
The DC antigen is one of the class II major histocompatibility antigens involved in the regulation of the immune response. This… Expand
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