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Major Histocompatibility Complex, Class II, DP Beta 1

Known as: human histocompatibility complex derived antigens-DPB1, HLA DPB1, HLA Class II Histocompatibility Antigen, DP(W4) Beta Chain 
HLA class II histocompatibility antigen, DP(W4) beta chain (258 aa, ~29 kDa) is encoded by the human HLA-DPB1 gene. This protein plays a role in… 
National Institutes of Health

Related topics

Related topics

16 relations
Antigen PresentationCD4 Positive T LymphocytesCytoplasmic DomainGenes, MHC Class II

Broader (1)

HLA-DP Antigens

Papers overview

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Highly Cited
2010
Highly Cited
2010
A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis
We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple… 
Highly Cited
2004
Highly Cited
2004
New genomic region for Wegener’s granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes
Wegener’s granulomatosis (WG) is a systemic disease with complex genetic background. It is characterized by necrotizing… 
Highly Cited
2003
Highly Cited
2003
Evolutionary stability of MHC class II haplotypes in diverse rhesus macaque populations
A thoroughly characterized breeding colony of 172 pedigreed rhesus macaques was used to analyze exon 2 of the polymorphic Mamu… 
Review
2003
Review
2003
HLA-DPB1 and chronic beryllium disease: a HuGE review.
The human leukocyte antigen (HLA) complex is a series of genes located on chromosome 6 that are important in normal immune… 
Highly Cited
2001
Highly Cited
2001
The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1.
The major histocompatibility complex (MHC) HLA region on chromosome 6p21 contains the major locus of type 1 diabetes (IDDM1… 
Review
2001
Review
2001
Differential evolutionary MHC class II strategies in humans and rhesus macaques: relevance for biomedical studies
Summary: The rhesus macaque is an important preclinical model in transplantation research and in investigations of chronic and… 
Highly Cited
2001
Highly Cited
2001
Association of chronic lymphocytic leukemia with specific alleles of the HLA‐DR4:DR53:DQ8 haplotype in German patients
The etiology of chronic lymphocytic leukemia (CLL) remains unknown, though a genetic susceptibility has been suggested. Results… 
Highly Cited
1999
Highly Cited
1999
Differential susceptibilities to chronic beryllium disease contributed by different Glu69 HLA-DPB1 and -DPA1 alleles.
Chronic beryllium disease (CBD) is associated with the allelic substitution of a Glu69 in the HLA-DPB1 gene. Although up to 97… 
Highly Cited
1996
Highly Cited
1996
Acute graft versus host disease due to T lymphocytes recognizing a single HLA-DPB1*0501 mismatch.
Analysis of a large number of unrelated bone marrow transplantations (BMT) has shown that HLA-DP incompatibility did not… 
Highly Cited
1995
Highly Cited
1995
Association to HLA-DRB1*08, HLA-DPB1*0301 and homozygosity for an HLA-linked proteasome gene in juvenile ankylosing spondylitis.
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