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Macrophage-1 Antigen

Known as: Integrin Alpha-M/Beta-2, Mac 1, Mac-1 Antigen 
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN… 
National Institutes of Health

Related topics

Related topics

17 relations
CD11b AntigensCD18 AntigensCell AdhesionCell Adhesion Molecules

Broader (1)

Receptors, Leukocyte-Adhesion

Papers overview

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Highly Cited
1999
Highly Cited
1999
PGG-glucan, a soluble beta-(1,3)-glucan, enhances the oxidative burst response, microbicidal activity, and activates an NF-kappa B-like factor in human PMN: evidence for a glycosphingolipid beta-(1,3…
PGG-Glucan, a soluble beta-(1,6)-branched beta-(1,3)-linked glucose homopolymer derived from the cell wall of the yeast… 
Highly Cited
1996
Highly Cited
1996
Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization.
Previous studies have shown that the leukocyte integrin CR3 (CD11b/CD18) is physically associated with the urokinase-type… 
Highly Cited
1995
Highly Cited
1995
In vivo state of antiviral CTL precursors. Characterization of a cycling cell population containing CTL precursors in immune mice.
The in vivo state of CD8+ mouse memory CTL specific to lymphocytic choriomeningitis virus (LCMV) was characterized. During acute… 
Highly Cited
1994
Highly Cited
1994
A beta-glucan inhibitable zymosan receptor on channel catfish neutrophils.
Highly Cited
1992
Highly Cited
1992
Analysis of cytokine mRNA levels in interleukin‐4‐transgenic mice by quantitative polymerase chain reaction
Interleukin (IL)‐4‐transgenic mice were used as a model system to study the consequences of low levels of IL‐4 expression for the… 
Highly Cited
1989
Highly Cited
1989
Induction of tumor-specific in vivo protective immunity by immunization with tumor antigen-pulsed antigen-presenting cells.
The present study investigates the role of APC in inducing tumor-specific in vivo protective immunity. Thy-1+ cell-depleted, Mac… 
Highly Cited
1987
Highly Cited
1987
In vivo inhibition of neutrophil function in the rabbit using monoclonal antibody to CD18.
The CD11b/CD18 membrane antigen complex has been shown to be essential for normal neutrophil function in vitro, and patients… 
Highly Cited
1986
Highly Cited
1986
LFA-1 immunodeficiency disease. Definition of the genetic defect and chromosomal mapping of alpha and beta subunits of the lymphocyte function-associated antigen 1 (LFA-1) by complementation in…
Lymphocyte function associated antigen 1 (LFA-1) is a leukocyte cell adhesion protein. We have studied a novel human… 
Highly Cited
1984
Highly Cited
1984
A unique series of lymphomas related to the Ly-1+ lineage of B lymphocyte differentiation.
Six new B lineage lymphomas of NFS mice established in primary tissue culture were examined for a number of phenotypic… 
Highly Cited
1983
Highly Cited
1983
Biosynthesis and assembly of the alpha and beta subunits of Mac-1, a macrophage glycoprotein associated with complement receptor function.
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