Macrocytosis (morphologic abnormality)

Known as: Karyocytomegaly, megalocytosis 
An increase in nuclear size and amount of cytoplasm of a cell. The cells or nucleus may be slightly irregular and/or may be polyploid.

Topic mentions per year

Topic mentions per year

1962-2016
02419622016

Papers overview

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2012
2012
During the past decade, the zebrafish has emerged as a leading model for mechanistic cancer research because of its sophisticated… (More)
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2007
2007
We studied the hepatocellular alterations induced by sub-lethal concentrations (0.50 muM) of arsenic in Indian catfish Clarias… (More)
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2006
2006
The pyrrolizidine alkaloid monocrotaline (MCT) initiates pulmonary hypertension by inducing a "megalocytosis" phenotype in target… (More)
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2005
2005
Pyrrolizidine alkaloids initiate disease in the lung (pulmonary hypertension), liver (veno-occlusive disease and cirrhosis), and… (More)
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2004
2004
BACKGROUND In the monocrotaline (MCT)-treated rat, there is marked stimulation of DNA synthesis and megalocytosis of pulmonary… (More)
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2004
2004
Background—In the monocrotaline (MCT)-treated rat, there is marked stimulation of DNA synthesis and megalocytosis of pulmonary… (More)
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1999
1999
BACKGROUND/AIM We have designed an experimental model in which transplantation of normal hepatocytes into rats previously treated… (More)
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1995
1995
Lasiocarpine (LC), a pyrrolizidine alkaloid, is able to induce a series of chronic and progressive lesions in rat liver… (More)
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1981
1981
Monocrotaline, a pyrrolizidine alkaloid derived from Crotalaria spectabilis, is known to be toxic to a variety of domestic and… (More)
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1975
1975
Male Fischer rats, 6 weeks old, were injected once with one of five doses of azoxymethane. There was a dose response to the… (More)
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