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Macrocytosis (morphologic abnormality)

Known as: Karyocytomegaly, megalocytosis 
An increase in nuclear size and amount of cytoplasm of a cell. The cells or nucleus may be slightly irregular and/or may be polyploid.
National Institutes of Health

Related topics

Related topics

8 relations
Abnormal Red Blood CellCDISC SEND Non-Neoplastic Finding Type TerminologyClinical Data Interchange Standards Consortium TerminologyMacrocyte Count procedure

Broader (2)

Anemia, Macrocyticred blood cell disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Hepatic megalocytosis due to vanadium inhalation: participation of oxidative stress
The aim of this study was to evaluate the morphological changes, liver function test (LFT), and oxidative stress damage caused by… 
1999
1999
Progression of hepatic neoplasia in medaka (Oryzias latipes) exposed to diethylnitrosamine.
Progression of hepatic neoplasia was assessed in medaka (Oryzias latipes) following aqueous exposure to diethylnitrosamine (DEN… 
1999
1999
Hepatotoxicity associated with pyrrolizidine alkaloid (Crotalaria spp) ingestion in a horse on Easter Island.
Since 1984, a significant number of privately owned and feral horses on Easter Island have died of a syndrome consisting of… 
1988
1988
Suspected toxicopathic hepatic necrosis and megalocytosis in pen-reared Atlantic salmon Salmo salar in Puget Sound, Washington, USA.
Severe liver disease was associated with mortality in Atlantic salmon Salmo salar maintained in seawater net pens in Port… 
1985
1985
Initiation and selection of resistant hepatocyte nodules in rats given the pyrrolizidine alkaloids lasiocarpine and senecionine.
The biological mechanisms by which pyrrolizidine alkaloids contribute to initiation and nodule selection (promotion) steps in… 
1984
1984
Cynoglossum officinale (hound's-tongue)--a cause of pyrrolizidine alkaloid poisoning in horses.
The death of 10 horses was attributed to feeding dried grass hay containing hound's-tongue, Cynoglossum officinale. Affected… 
1977
1977
Intestinal lesions induced experimentally by methotrexate.
Mice were given up to 9 doses of methotrexate intermittently over a 3-week period. Inhibition of mitosis occurred in the duodenum… 
1975
1975
Streptozotocin-induced diabetes mellitus and the host-parasite relation in murine schistosomiasis mansoni.
The effect of streptozotocin-induced diabetes mellitus on both the host and the parasite was studied in mice infected with… 
Highly Cited
1969
Highly Cited
1969
The development of the hepatic megalocytosis of chronic pyrrolizidine alkaloid poisoning.
CHRONI POISoNwIG by a hepatotoxic pyrroliz:idine alkaloid 1" produces a liver lesion c by megalocytosis of the liver parenchyma… 
1968
1968
Development of hepatic lesions in calves fed with ragwort (Senecio jacobea).
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