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MYOC gene

Known as: juvenile-onset open-angle glaucoma 1, TIGR, MYOCILIN 
National Institutes of Health

Related topics

Related topics

3 relations
GLAUCOMA 1, OPEN ANGLE, AMYOC protein, humantrabecular meshwork-induced glucocorticoid response protein

Papers overview

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Highly Cited
2014
Highly Cited
2014
Proteomic Differences between Male and Female Anterior Cruciate Ligament and Patellar Tendon
The risk of anterior cruciate ligament (ACL) injury and re-injury is greater for women than men. Among other factors… 
Highly Cited
2009
Highly Cited
2009
Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte.
PURPOSE To characterize a novel Asp384Asn (D384N) mutant myocilin (MYOC) that causes juvenile-onset open-angle glaucoma (JOAG… 
2006
2006
Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure.
PURPOSE To characterize the changes in retinal gene expression induced by elevated intraocular pressure (IOP) in a hereditary… 
2006
2006
Perfusion of his-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor.
PURPOSE A previous study by the authors has shown that recombinant myocilin purified from a prokaryotic expression system… 
Highly Cited
2005
Highly Cited
2005
Myocilin binding to Hep II domain of fibronectin inhibits cell spreading and incorporation of paxillin into focal adhesions.
Highly Cited
2004
Highly Cited
2004
Overexpression of myocilin in cultured human trabecular meshwork cells.
2003
2003
Analysis of 15 primary open-angle glaucoma families from Australia identifies a founder effect for the Q368STOP mutation of myocilin
Abstract. Primary open-angle glaucoma (POAG) is a leading cause of blindness in the world. A number of mutations in the myocilin… 
2002
2002
Protein interactions with myocilin.
PURPOSE To identify factors that interact in vivo with myocilin, a glaucoma gene product. METHODS The yeast two-hybrid system… 
Highly Cited
2002
Highly Cited
2002
Myocilin is associated with mitochondria in human trabecular meshwork cells
The trabecular meshwork (TM) is a specialized tissue located at the chamber angle of the eye next to the cornea. This tissue is… 
2000
2000
Localization of myocilin to the golgi apparatus in Schlemm's canal cells.
PURPOSE Biochemical and genetic evidence suggests that overexpression of or mutations in myocilin within the cells of the aqueous… 
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