MYOC gene

Known as: juvenile-onset open-angle glaucoma 1, TIGR, MYOCILIN 
 
National Institutes of Health

Papers overview

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2008
2008
PURPOSE To investigate the role of MYOC and CYP1B1 in Iranian juvenile open angle glaucoma (JOAG) patients. METHODS Twenty… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Mutations in the CYP1B1, MYOC, OPTN, and WDR36 genes result in glaucoma. Given its expression in the optic nerve, it is… (More)
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Highly Cited
2004
Highly Cited
2004
Despite the importance of MYOC for glaucoma, the protein's normal function(s) and the pathogenic mechanism(s) of MYOC mutations… (More)
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Review
2002
Review
2002
Mutations in the MYOC gene that encodes for myocilin are causative for some forms of juvenile and adult-onset primary open-angle… (More)
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Highly Cited
2001
Highly Cited
2001
Glaucoma is a heterogeneous eye disease and a major cause of blindness worldwide. Recently, primary open angle glaucoma (POAG… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To examine the intracellular and extracellular expression of myocilin in the human and primate trabecular meshwork (TM… (More)
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Highly Cited
2001
Highly Cited
2001
Until recently, very little was known about the molecular mechanisms responsible for the development of glaucoma, a leading cause… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE Glucocorticoid-induced ocular hypertension (the steroid response) may result in optic nerve damage that very closely… (More)
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2000
2000
PURPOSE To evaluate MYOC (myocilin) gene expression at the RNA level in normal intact human eyes and optic nerve using in situ… (More)
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1998
1998
PURPOSE The aim of this study was to screen affected members of glaucoma families for mutations in the Trabecular Meshwork… (More)
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