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MYD88 NP_002459.2:p.L265P

Known as: MYD88 L265P, MYD88 p.L265P, NP_002459.2:p.Leu265Pro 
A change in the amino acid residue at position 265 in the myeloid differentiation primary response protein MyD88 where leucine has been replaced by… 
National Institutes of Health

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Related topics

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MYD88 Gene Mutation

Papers overview

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2018
2018
HSP 110 sustains chronic NF-κB signaling in activated B cell diffuse large B cell lymphoma through MyD 88 stabilization Running title : HSP 110 sustains chronic NF-κB signaling
2018
2018
MYD88 L265P mutation in primary and relapsed CNS DLBCL patients
2018
2018
华氏巨球蛋白血症相关突变 MYD88 L265P新型检测体系的建立
2016
2016
Abstract 346: Potential role for R191, potent and selective IRAK4 kinase inhibitor, in treatment of hematologic malignancies
Recent advances in genome sequencing and tumor proteome and transcriptome analysis uncovered a key role for MyD88-dependent Toll… 
2015
2015
Waldenstrom Macroglobulinemia an Auto-inflammatory Syndrome? Efficacy of Tocilizumab: A Case Report
Waldenstrom macroglobulinemia is a lymphoplasmocytic lymphoma involving bone marrow and characterized by the production of a… 
2013
2013
PI3K/AKT Pathway Is Activated By MYD88 L265P and Use Of PI3K-Delta Inhibitors Induces Robust Tumor Cell Killing In Waldenstrom’s Macroglobulinemia
Background MYD88 L265P is a somatic mutation present in >90% of Waldenstrom's Macroglobulinemia (WM) patients. The downstream… 
2013
2013
polymerase chain reaction disorders using conventional and quantitative allele-specific monoclonal gammopathy, and other B-cell lymphoproliferative MYD88 L265P in Waldenström macroglobulinemia…
2012
2012
MYD88 L265P Promotes Survival of Waldenstrom's Macroglobulinemia Cells by Activation of Bruton's Tyrosine Kinase
Abstract 897 Background: MYD88 is an adapter molecule which promotes Toll-Like Receptor and IL-1 Receptor signaling through the… 
2011
2011
Disruption of MYD88 Pathway Signaling Leads to Loss of Constitutive IRAK1, NF-κβ and JAK/STAT Signaling and Induces Apoptosis of Cells Expressing the MYD88 L265P Mutation in Waldenstrom's…
Abstract 597 Introduction: Through whole genome sequencing of bone marrow lymphoplasmacytic cells (LPCs) from WM patients, we… 
2006
2006
[Transfection of dominant negative MyD88 decreases IL-8 production in bacteria-infected airway epithelial cells].
Interleukin-8 (IL-8) is an important activator and chemoattratant of neutrophils and has been implicated in airway inflammatory…