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MYD88 NP_002459.2:p.L265P

Known as: MYD88 L265P, MYD88 p.L265P, NP_002459.2:p.Leu265Pro 
A change in the amino acid residue at position 265 in the myeloid differentiation primary response protein MyD88 where leucine has been replaced by… 
National Institutes of Health

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Related topics

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MYD88 Gene Mutation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P–Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases
Purpose: MYD88 mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of activated B-cell… 
Review
2015
Review
2015
The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing
Plasmacytic differentiation may occur in almost all small B cell lymphomas (SBLs), although it varies from being uniformly… 
Review
2015
Review
2015
MYD88 L265P mutation analysis helps define nodal lymphoplasmacytic lymphoma
The diagnosis of lymphoplasmacytic lymphoma is often challenging, especially in extramedullary tissues where the differential… 
Highly Cited
2015
Highly Cited
2015
MYD88 L265P and CXCR4 mutations in lymphoplasmacytic lymphoma identify cases with high disease activity
Recurrent mutations in MYD88 have been identified in >90% of lymphoplasmacytic lymphoma (LPL). Recently, WHIM (warts… 
Highly Cited
2014
Highly Cited
2014
Kaposi's Sarcoma-Associated Herpesvirus-Encoded Replication and Transcription Activator Impairs Innate Immunity via Ubiquitin-Mediated Degradation of Myeloid Differentiation Factor 88
ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus with latent and lytic reactivation cycles… 
Highly Cited
2014
Highly Cited
2014
Anti-inflammatory effects of cordycepin in lipopolysaccharide-stimulated RAW 264.7 macrophages through Toll-like receptor 4-mediated suppression of mitogen-activated protein kinases and NF-κB…
Cordycepin is the main functional component of the Cordyceps species, which has been widely used in traditional Oriental medicine… 
Highly Cited
2013
Highly Cited
2013
MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase…
By whole-genome and/or Sanger sequencing, we recently identified a somatic mutation (MYD88 L265P) that stimulates nuclear factor… 
Highly Cited
2009
Highly Cited
2009
Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner1
Neurological deficits in children, including cerebral palsy, are associated with prior infection during the perinatal period… 
Highly Cited
2008
Highly Cited
2008
Central Role of MyD88-Dependent Dendritic Cell Maturation and Proinflammatory Cytokine Production to Control Brucella abortus Infection1
Brucella abortus is a facultative intracellular bacterium that infects humans and domestic animals. The enhanced susceptibility… 
Highly Cited
2003
Highly Cited
2003
Mycobacterial Infection in MyD88‐Deficient Mice
MyD88 is an adaptor protein that plays a major role in TLR/IL‐1 receptor family signaling. To understand the role of MyD88 in the… 
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