MYCN wt Allele

Known as: NMYC, v-MYC Myelocytomatosis Viral Related Oncogene, Neuroblastoma Derived (Avian) wt Allele, MODED 
Human MYCN wild-type allele is located in the vicinity of 2p24.1 and is approximately 6 kb in length. This allele, which encodes N-myc proto-oncogene… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Sonic Hedgehog (SHH) signaling drives a minority of… (More)
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Highly Cited
2008
Highly Cited
2008
Amplified MYCN oncogene resulting in deregulated MYCN transcriptional activity is observed in 20% of neuroblastomas and… (More)
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Highly Cited
2004
Highly Cited
2004
CD1d-restricted Valpha24-Jalpha18-invariant natural killer T cells (iNKTs) are potentially important in tumor immunity. However… (More)
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Highly Cited
2003
Highly Cited
2003
Cerebellar granule cells are the most abundant neurons in the brain, and granule cell precursors (GCPs) are a common target of… (More)
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Highly Cited
2002
Highly Cited
2002
CONTEXT Brain tumors are the most common solid tumor in childhood, and medulloblastoma is the most common malignant brain tumor… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE A prospective Children's Cancer Group study, CCG-3881, has been completed to determine if a more accurate prediction of… (More)
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Highly Cited
1999
Highly Cited
1999
Deletions of the long arm of chromosome 11 (11q) have been noted in primary neuroblastomas, but a comprehensive analysis has not… (More)
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Highly Cited
1997
Highly Cited
1997
The proto-oncogene MYCN is often amplified in human neuroblastomas. The assumption that the amplification contributes to… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND AND METHODS The nerve growth factor receptor is expressed in some neuroblastomas, in which its primary component is… (More)
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Highly Cited
1985
Highly Cited
1985
Eighty-nine patients with untreated primary neuroblastomas were studied to determine the relation between the number of copies of… (More)
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