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MXI1 gene

Known as: MAX Interactor 1 Gene, bHLHc11, MAD2 
This gene plays a role in regulation of transcription and mitosis. It is also involved in terminal differentiation.
National Institutes of Health

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MAX Interacting Protein 1Transcriptional RegulationTranscriptional Repression

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MXI1 wt Allele

Papers overview

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2008
2008
Molecular and cellular mechanisms of invasion of the intestinal barrier by enteric pathogens the paradigm ofShigella
The pathogenesis of bacillary dysentery can be studied at different levels of integration of the cellular components that… 
2007
2007
Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia
The Myc antagonists Mad1, Mxi1 and Rox proteins share two highly conserved domains, Sin3-interacting domain (SID) and basic helix… 
2006
2006
Temporal transcriptome of mouse ATDC5 chondroprogenitors differentiating under hypoxic conditions.
2005
2005
Mxi1 isoforms are expressed in hematological cell lines and normal bone marrow.
Mxi1 protein is a basic helix-loop-helix, leucine zipper (bHLHZIP) transcriptional factor, which dimerizes with the Max protein… 
2004
2004
Autoregulation of the N‐myc gene is operative in neuroblastoma and involves histone deacetylase 2
Autoregulation of the myc gene family is a negative feedback mechanism known to occur at high levels of Myc expression. Loss of… 
Review
1999
Review
1999
Two MAD tails: what the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network.
Review
1998
Review
1998
Molecular bases of epithelial cell invasion by Shigella flexneri
The pathogenesis of shigellosis is characterized by the capacity of the causative microorganism, Shigella, to invade the… 
1996
1996
Genomic organization of human MXI1, a putative tumor suppressor gene.
MXI1, a member of the MYC family of transcription factors, is thought to negatively regulate MYC function and may therefore be a… 
1995
1995
Redefinition of the coding sequence of the MXI1 gene and identification of a polymorphic repeat in the 3′ non-coding region that allows the detection of loss of heterozygosity of chromosome 10q25 in…
The MXI1 gene encodes a protein interacting with Max, a regulatory factor of the Myc oncogene, and is located on chromosome 10q25… 
1994
1994
Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25.
MAD and MXI1, two recently described members of the basic helix-loop-helix (bHLH) gene family, encode proteins that dimerize with… 
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