MUC16 gene

Known as: mucin 16, cell surface associated, CA125, MUCIN 16 
This gene is involved in both cellular adhesion and the maintenance of mucosal surfaces.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye disease (DED). The Subcommittee reviewed… (More)
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2012
2012
MUC16/CA125 is a tumor marker currently used in clinics for the follow-up of patients with ovarian cancer. However, MUC16… (More)
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Highly Cited
2011
Highly Cited
2011
MUC16 (CA125) belongs to a family of high-molecular weight O-glycosylated proteins known as mucins. While MUC16 is well known as… (More)
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Highly Cited
2009
Highly Cited
2009
Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on… (More)
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Highly Cited
2008
Highly Cited
2008
Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse systemic effects of potent cytotoxic… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE The membrane-associated mucin MUC16, a heavily O-glycosylated transmembrane protein, is expressed by the ocular surface… (More)
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Highly Cited
2006
Highly Cited
2006
The mucin MUC16 and the glycosylphosphatidylinositol anchored glycoprotein mesothelin likely facilitate the peritoneal metastasis… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE H185 antibody has been shown to recognize a carbohydrate epitope on a membrane-associated mucin in the apical surfaces of… (More)
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Highly Cited
2002
Highly Cited
2002
Serum assays based on the CA125 antigen are widely used in the monitoring of patients with ovarian cancer; however very little is… (More)
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Highly Cited
2001
Highly Cited
2001
CA125 is an ovarian cancer antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian… (More)
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