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Mucin-16

Known as: Ovarian Carcinoma Antigen CA125, Ovarian Cancer-Related Tumor Marker CA125, CA-125 
Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of… 
National Institutes of Health

Related topics

Related topics

6 relations
CA 125 measurementCA-125 AntigenCell AdhesionEpithelial Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Sorafenib in Combination With Gemcitabine in Recurrent Epithelial Ovarian Cancer: A Study of the Princess Margaret Hospital Phase II Consortium
Objectives: Antiangiogenic strategies have demonstrated efficacy in epithelial ovarian cancer (EOC). Sorafenib is a novel… 
Highly Cited
2007
Highly Cited
2007
Proteomic Profiling Identifies Afamin as a Potential Biomarker for Ovarian Cancer
Purpose: To discover and validate serum glycoprotein biomarkers in ovarian cancer using proteomic-based approaches. Experimental… 
Highly Cited
2002
Highly Cited
2002
Allogeneic hematopoietic stem cell transplantation in ovarian carcinoma: results of five patients
Allogeneic hematopoietic stem cell transplantation is often used to treat hematologic malignancies. The efficacy of this… 
Review
2001
Review
2001
Effective palliative radiation therapy in advanced and recurrent ovarian carcinoma.
Highly Cited
1993
Highly Cited
1993
Ovarian Cancer Screening in Asymptomatic Postmenopausal Women
Abstract From 1987 to 1992, 3220 asymptomatic postmenopausal women underwent screening with transvaginal sonography (TVS) as part… 
Highly Cited
1993
Highly Cited
1993
OVX1 radioimmunoassay complements CA-125 for predicting the presence of residual ovarian carcinoma at second-look surgical surveillance procedures.
PURPOSE At second-look surgical surveillance procedures, normal CA-125 levels can be associated with persistent disease in 50% to… 
1993
1993
High serum and ascitic soluble interleukin-2 receptor alpha levels in advanced epithelial ovarian cancer.
This study was undertaken to determine if advanced epithelial ovarian cancer was associated with increased serum and ascitic… 
Highly Cited
1990
Highly Cited
1990
Pretreatment serum levels of CA-125, carcinoembryonic antigen, tissue polypeptide antigen, and placental alkaline phosphatase, in patients with ovarian carcinoma, borderline tumors, or benign adnexal…
Highly Cited
1989
Highly Cited
1989
Use of CA-125 to predict survival of patients with ovarian carcinoma. North Thames Cooperative Group.
The prognostic value of serum CA-125 measurements was assessed in 54 patients with advanced ovarian adenocarcinoma. All patients… 
Highly Cited
1986
Highly Cited
1986
CA-125 levels in endometriosis.
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