Mucin-16

Known as: Ovarian Carcinoma Antigen CA125, Ovarian Cancer-Related Tumor Marker CA125, CA-125 
Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
INTRODUCTION Ovarian cancer is associated with high mortality due to presentation at advanced stage and high recurrence following… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE The progression-free and median survival of patients with advanced ovarian cancer has not appreciably improved over the… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To determine the utility of serum miRNAs as biomarkers for epithelial ovarian cancer. METHODS Twenty-eight patients… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Early detection would significantly decrease the mortality rate of ovarian cancer. In this study, we characterize and… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Ovarian cancers (OCs) frequently have HER2 activation in the absence of HER2 overexpression. Pertuzumab, a humanized… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Ovarian cancer screening with transvaginal ultrasound (TVU) and CA-125 was evaluated in the Prostate, Lung, Colorectal… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chemotherapy with a platinum agent and a taxane (paclitaxel) is considered the standard of care for treatment of… (More)
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Highly Cited
2003
Highly Cited
2003
A large number of cancer-associated gene products evoke immune recognition, but host reactions rarely impede disease progression… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnosis and prognosis may ultimately… (More)
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Review
2003
Review
2003
One of the most promising approaches to management of ovarian cancer is early detection. Stage I ovarian cancer can be cured with… (More)
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