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MTTP wt Allele

Known as: Microsomal Triglyceride Transfer Protein (Large Polypeptide, 88kD) Gene, Microsomal Triglyceride Transfer Protein (Large Polypeptide, 88kDa) Gene, Microsomal Triglyceride Transfer Protein wt Allele 
Human MTTP wild-type allele is located in the vicinity of 4q24 and is approximately 60 kb in length. This allele, which encodes microsomal… 
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensLigand BindingLipid BindingLipid Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Mechanisms underlying hypertriglyceridemia in rats with monosodium L-glutamate-induced obesity: evidence of XBP-1/PDI/MTP axis activation.
Review
2014
Review
2014
Potential Approaches to Ameliorate Hepatic Fat Accumulation Seen with MTP Inhibition
Microsomal triglyceride transfer protein (MTP) is one of the promising targets for the therapy of dyslipidemia and MTP inhibition… 
2011
2011
Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide.
2007
2007
Nonalcoholic Steatohepatitis (NASH) in OB/OB Mice Treated with Yo Jyo Hen Shi Ko (YHK): Effects on Peroxisome Proliferator-Activated Receptors (PPARs) and Microsomal Triglyceride Transfer Protein…
YHK has antioxidant properties, has a hypoglycemic effect, and may reduce plasma lipid levels. In this study, we examined the… 
Review
2005
Review
2005
Current biology of MTP: implications for selective inhibition.
The microsomal triglyceride transfer protein (MTP), along with its partner, protein disulphide isomerase, performs a wide range… 
2005
2005
Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance.
Hepatic lipoprotein overproduction in a fructose-fed hamster model of insulin resistance was previously shown to be associated… 
2005
2005
Maternal heterozygosity for a mitochondrial trifunctional protein mutation as a cause for liver disease in pregnancy.
2003
2003
Deletion of the 5'ABL Region in Philadelphia Chromosome Positive Chronic Myeloid Leukemia: Frequency, Origin and Prognosis
The use of new nuclei probes in fluorescent in situ hybridization (FISH) at diagnosis and during follow up has recently allowed… 
2002
2002
Regulation of MTP expression in developing swine DOI 10.1194/jlr.M200035-JLR200
To define the developmental expression of microsomal triglyceride transfer protein (MTP) large subunit mRNA and protein, samples… 
1998
1998
Identification of two polymorphisms in the promoter of the microsomal triglyceride transfer protein (MTP) gene: lack of association with lipoprotein profiles.
The microsomal triglyceride transfer protein (MTP) catalyzes the transfer of triglyceride, cholesteryl ester, and… 
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