MTP-131
National Institutes of Health
Papers overview
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Exposure to chronic hyperglycemia because of diabetes mellitus can lead to development and progression of diabetic kidney disease…
Objective To assess the safety and efficacy of elamipretide, an aromatic-cationic tetrapeptide that readily penetrates cell…
Background—Elamipretide (MTP-131), a novel mitochondria-targeting peptide, was shown to reduce infarct size in animals with…
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The management and, as a consequence, the…
ABSTRACT Diabetic retinopathy is characterized by progressive vision loss and the advancement of retinal micoraneurysms, edema…
Background: The heat shock protein H11 kinase (H11K) is expressed in the heart of dogs, rodents and humans and rapidly increases…
Introduction: An inflammatory state exists in heart failure (HF) evidenced by elevated cytokines including tumor necrosis factor…
Introduction: The heat shock protein H11 kinase (H11K) is expressed in the heart and rapidly increases in response to increased…
PURPOSE
To investigate the antioxidative ability of a novel mitochondria-targeted peptide MTP-131 in immortalized human…