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MTHFR gene

Known as: methylenetetrahydrofolate reductase gene, 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE, MTHFR 
This gene is involved in folate metabolism and methionine biosynthesis.
National Institutes of Health

Related topics

Related topics

5 relations
5,10-Methylenetetrahydrofolate Reductase (FADH2)Methylenetetrahydrofolate reductase (NADPH)Oxidation-Reductionfolic acid metabolism

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
MTHFR polymorphisms and breast cancer risk
Introduction Two functional single nucleotide polymorphisms (SNPs) in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene… 
Review
2009
Review
2009
Methylenetetrahydrofolate reductase gene polymorphism and childhood stroke.
2004
2004
The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin…
2002
2002
The Association Between Inherited Thrombophilia, Antiphospholipid Antibodies and Lipoprotein A Levels with Obstetrical Complications in Pregnancy
AbstractObjectives: To evaluate the association between obstetrical complications in pregnancy and thrombophilic factors. Study… 
2000
2000
Prevalence of prothrombin 20210A allele and methylenetetrahydrofolate reductase C677T genetic mutations in the Chinese population
Abstract From July 1997 to June 1998, a total of 1323 subjects, including 1180 controls, 94 patients with diabetes mellitus, and… 
Highly Cited
2000
Highly Cited
2000
Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese women.
An association between preeclampsia (PE) and a common missense mutation of the methylenetetrahydrofolate reductase gene (MTHFR… 
Highly Cited
1998
Highly Cited
1998
A common methylenetetrahydrofolate reductase gene mutation and longevity.
Highly Cited
1997
Highly Cited
1997
A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of coronary artery disease or myocardial infarction.
1997
1997
Elevated plasma total homocysteine and C677T mutation of the methylenetetrahydrofolate reductase gene in patients with spina bifida.
Total plasma homocysteine (tHcy) was significantly higher in 28 children with spina bifida (median 6.05 mumol/l) as compared with… 
Highly Cited
1976
Highly Cited
1976
Morphologic Studies in a Patient with Homocystinuria due to 5,10-Methylenetetrahydrofolate Reductase Deficiency
Extract: Biochemical and morphologic studies on a patient with homocystinuria due to a deficiency of 5,10… 
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