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MTHFD1 wt Allele

Known as: MTHFC, MTHFD, Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase wt Allele 
Human MTHFD1 wild-type allele is located in the vicinity of 14q24 and is approximately 72 kb in length. This allele, which encodes C-1… 
National Institutes of Health

Related topics

Related topics

4 relations
14q24HydrolysisOxidation-Reductionfolic acid metabolism

Papers overview

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2019
2019
Molecular structure of a 5,10‐methylenetetrahydrofolate dehydrogenase from the silkworm Bombyx mori
The enzyme 5,10‐methylenetetrahydrofolate dehydrogenase (MTHFD) is essential for the production of certain amino acids (glycine… 
2018
2018
Diagnostic approach to neurotransmitter monoamine disorders: experience from clinical, biochemical, and genetic profiles
Background and aimTo improve the diagnostic work-up of patients with diverse neurological diseases, we have elaborated specific… 
2018
2018
Vitamin D and folate: A reciprocal environmental association based on seasonality and genetic disposition
The purpose of this study was (1) to elucidate any reciprocal seasonal relationship that might exist between red cell folate (RCF… 
2018
2018
MTHFR and MTHFD1 gene polymorphisms are not associated with pseudoexfoliation syndrome in South Indian population
PurposePseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with… 
Review
2015
Review
2015
Is MTHFD1 polymorphism rs 2236225 (c.1958G>A) associated with the susceptibility of NSCL/P? A systematic review and meta-analysis
Aims: To investigate the association between the methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) polymorphism rs 2236225 (c… 
2011
2011
Head and neck carcinogenesis : impact of MTHFD 1 G 1958 A polymorphism
Objective: To investigate the MTHFD1 G1958A polymorphism involved in the folate metabolism as a risk for head and neck cancer… 
2007
2007
Polymorphisms of MTHFD, plasma homocysteine levels, and risk of gastric cancer in a high-risk Chinese population
Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate… 
1998
1998
Dominant defects in Drosophila eye pigmentation resulting from a euchromatin-heterochromatin fusion gene.
We have isolated a dominant mutation, pugilistDominant (pugD), that causes variegated reductions in pteridine and ommochrome… 
1991
1991
A pseudogene on the X chromosome for the human trifunctional enzyme MTHFD (methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase).
1991
1991
Deficient synthesis of MTHFD, a trifunctional folate-dependent enzyme, in the CHO Ade−E mutant
MTHFD is a folate-dependent trifunctional protein comprised of three activities: N5,N10-methylenetetrahydrofolate dehydrogenase… 
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