MSTN gene

Known as: GROWTH/DIFFERENTIATION FACTOR 8, MYOSTATIN, Myostatin Gene 
This gene plays a role in cell differentiation and the regulation of transcription. It is also involved in the regulation of muscle mass.
National Institutes of Health

Papers overview

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2015
2015
Recent advances in the study of the CRISPR/Cas9 system have provided a precise and versatile approach for genome editing in… (More)
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Highly Cited
2010
Highly Cited
2010
Variants of the MSTN gene encoding myostatin are associated with muscle hypertrophy phenotypes in a range of mammalian species… (More)
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Highly Cited
2009
Highly Cited
2009
The postovulatory rise in circulating progesterone (P4) concentrations is associated with increased pregnancy success in beef and… (More)
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Highly Cited
2008
Highly Cited
2008
Myostatin (MSTN) is a secreted growth inhibitor expressed in muscle and adipose. We sought to determine whether expression of… (More)
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2008
2008
Myostatin (MSTN), a transforming growth factor beta superfamily member, is an essential factor for the growth and development of… (More)
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Highly Cited
2007
Highly Cited
2007
Double muscling is a trait previously described in several mammalian species including cattle and sheep and is caused by… (More)
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Highly Cited
2006
Highly Cited
2006
Texel sheep are renowned for their exceptional meatiness. To identify the genes underlying this economically important feature… (More)
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Highly Cited
2002
Highly Cited
2002
Myostatin is a TGF-beta family member that acts as a negative regulator of muscle growth. Mice lacking the myostatin gene (Mstn… (More)
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Highly Cited
1999
Highly Cited
1999
Transgenic mice lacking a functional myostatin (MSTN) gene demonstrate greater skeletal muscle mass resulting from muscle fiber… (More)
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Highly Cited
1997
Highly Cited
1997
An exceptional muscle development commonly referred to as ‘double-muscled’ (Fig. 1) has been seen in several cattle breeds and… (More)
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