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GDF8 protein, human

Known as: Growth/Differentiation Factor 8, growth differentiation factor 8 protein, human, Myostatin 
Growth/differentiation factor 8 (375 aa, ~43 kDa) is encoded by the human MSTN gene. This protein plays a role in the negative regulation of skeletal… Expand
National Institutes of Health

Papers overview

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2017
2017
BackgroundGrowth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor… Expand
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2014
2014
Background: GDF8/myostatin suppresses myogenic differentiation. Results: The small molecule inhibitors dorsomorphin and LDN… Expand
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2012
2012
Average daily gain (ADG) and feed efficiency (FE) are important factors for assessing productivity in farm animals. Myostatin… Expand
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2010
2010
To the Editors: Quadriceps muscle dysfunction is well recognised in chronic obstructive pulmonary disease (COPD), and is… Expand
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Highly Cited
2007
Highly Cited
2007
Myostatin (GDF8) is a negative regulator of skeletal muscle growth and mice lacking myostatin show a significant increase in… Expand
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2006
2006
Myostatin (GDF8) is a negative regulator of muscle growth in mammals, and loss-of-function mutations are associated with… Expand
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2006
2006
Myostatin is a transforming growth factor-beta (TGF-beta) superfamily member and a key negative regulator of embryonic and… Expand
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2005
2005
We have investigated muscle-bone interactions using two mouse mutants that are known to differ from normal mice in skeletal… Expand
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Highly Cited
2001
Highly Cited
2001
GDF-8 is a new member of the TGF-beta superfamily which appears to be a negative regulator of skeletal muscle mass. Factors which… Expand
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Highly Cited
1997
Highly Cited
1997
A visibly distinct muscular hypertrophy (mh), commonly known as double muscling, occurs with high frequency in the Belgian Blue… Expand
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