GDF8 protein, human

Known as: Growth/Differentiation Factor 8, growth differentiation factor 8 protein, human, Myostatin 
Growth/differentiation factor 8 (375 aa, ~43 kDa) is encoded by the human MSTN gene. This protein plays a role in the negative regulation of skeletal… (More)

Topic mentions per year

Topic mentions per year

1997-2018
0102019972018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Growth differentiation factor 11 (GDF11) and myostatin (or GDF8) are closely related members of the transforming growth factor… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Myostatin is a negative regulator of skeletal muscle size, previously shown to inhibit muscle cell differentiation. Myostatin… (More)
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Skeletal muscle fibrosis is a major pathological hallmark of chronic myopathies in which myofibers are replaced by progressive… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Myostatin, a transforming growth factor-beta (TGF-beta) super-family member, has been well characterized as a negative regulator… (More)
Is this relevant?
2006
2006
Obesity is associated with insulin resistance in skeletal muscle; accordingly, weight loss dramatically improves insulin action… (More)
  • table 1
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Myostatin is a negative regulator of muscle mass. The impact of myostatin deficiency on the contractile properties of healthy… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Myostatin (MSTN), a transforming growth factor (TGF)-beta superfamily member, has been shown to negatively regulate muscle growth… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Myostatin is a recently discovered member of the TGF-b superfamily of genes. It is expressed in skeletal muscle and… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The mechanism of the loss of skeletal muscle mass that occurs during spaceflight is not well understood. Myostatin has been… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2000
2000
Myostatin, a member of the TGF-beta superfamily, is a key negative regulator of skeletal muscle growth. The role of myostatin… (More)
Is this relevant?