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Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.
OBJECTIVE Our objective was to update the guidelines for the evaluation and treatment of androgen deficiency syndromes in adult men published previously in 2006. PARTICIPANTS The Task Force wasExpand
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Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.
Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable societal consequences for the development of frailty, disability, and health care planning. A group ofExpand
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Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.
OBJECTIVE The objective was to provide guidelines for the evaluation and treatment of androgen deficiency syndromes in adult men. PARTICIPANTS The Task Force was composed of a chair, selected byExpand
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The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.
BACKGROUND Athletes often take androgenic steroids in an attempt to increase their strength. The efficacy of these substances for this purpose is unsubstantiated, however. METHODS We randomlyExpand
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Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline.
Objective To update the "Testosterone Therapy in Men With Androgen Deficiency Syndromes" guideline published in 2010. Participants The participants include an Endocrine Society-appointed task forceExpand
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Adverse events associated with testosterone administration.
BACKGROUND Testosterone supplementation has been shown to increase muscle mass and strength in healthy older men. The safety and efficacy of testosterone treatment in older men who have limitationsExpand
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Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials.
BACKGROUND We performed a meta-analysis of randomized clinical trials to determine the risks of adverse events associated with testosterone replacement in older men. METHODS The MEDLINE databaseExpand
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Testosterone dose-response relationships in healthy young men.
Testosterone increases muscle mass and strength and regulates other physiological processes, but we do not know whether testosterone effects are dose dependent and whether dose requirements forExpand
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Clinical review 1: Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis.
CONTEXT The risks of testosterone therapy in men remain poorly understood. OBJECTIVE The aim of this study was to conduct a systematic review and meta-analyses of testosterone trials to evaluateExpand
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Sarcopenia with limited mobility: an international consensus.
A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered anExpand
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