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MRS 1754

Known as: MRS-1754, MRS1754 
National Institutes of Health

Papers overview

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2017
2017
A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives.
2015
2015
Adenosine A2B receptor activation stimulates glucose uptake in the mouse forebrain
ATP consumption during intense neuronal activity leads to peaks of both extracellular adenosine levels and increased glucose… 
2014
2014
The effects of adenosine A2B receptor inhibition on VEGF and nitric oxide axis-mediated renal function in diabetic nephropathy
Abstract Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. The pathophysiologic mechanisms… 
2011
2011
Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritis
Methotrexate (MTX) is widely utilized for the treatment of patients with rheumatoid arthritis (RA); however, recent observation… 
Highly Cited
2010
Highly Cited
2010
Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts.
Pre- and postconditioning depend on the activation of adenosine receptors (ARs) at the end of the index ischemia. The aim of this… 
2009
2009
Cardioprotection Induced by Adenosine A1 Receptor Agonists in a Cardiac Cell Ischemia Model Involves Cooperative Activation of Adenosine A2A and A2B Receptors by Endogenous Adenosine
Extracellular adenosine concentrations increase within the heart during ischemia, and any exogenous adenosine receptor agonists… 
2009
2009
A Volume Regulatory Response Can Be Triggered by Nucleosides in Human Erythrocytes, a Perfect Osmometer No Longer*
Human erythrocytes have been regarded as perfect osmometers, which swell or shrink as dictated by their osmotic environment. In… 
2009
2009
AMP579 is revealed to be a potent A2b-adenosine receptor agonist in human 293 cells and rabbit hearts
The mixed A1/A2a-adenosine agonist AMP579 given at reperfusion is protective in animal models of myocardial infarction. Receptor… 
Highly Cited
2005
Highly Cited
2005
The role of adenosine A2A and A2B receptors in the regulation of TNF-alpha production by human monocytes.
Highly Cited
2001
Highly Cited
2001
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists.
Novel 2-propynylcyclohexyl-5'-N:-ehtylcarboxamidoadenosines, trans-substituted in the 4-position of the cyclohexyl ring, were… 
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